ATRN and XRN2

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		ATRN	XRN2
Gene Name		attractin	5-3 exoribonuclease 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Nucleus Nucleolus Membrane Aggresome
	Molecular Function	Receptor Activity Carbohydrate Binding	Transcription Termination Site Sequence-specific DNA Binding Nuclease Activity 5'-3' Exoribonuclease Activity Zinc Ion Binding 5'-3' Exonuclease Activity Poly(A) RNA Binding
	Biological Process	Inflammatory Response Response To Oxidative Stress Cerebellum Development Regulation Of Multicellular Organism Growth Myelination Pigmentation	DNA Catabolic Process, Exonucleolytic DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated RNA Processing MRNA Processing RNA Catabolic Process Spermatogenesis Cell Growth RNA Metabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways			Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: COPS5 XRN2 ZNF408	24 interactors: ALDH1B1 ATRN COMT CSNK2A1 CTSC DISC1 DXO EEF1A1 EIF3L EIF5A EIF6 ERG EXOSC10 EXOSC8 LSM3 MOCS3 MRPL4 MRPS10 PRAME PSMA3 TARDBP TIPARP TOLLIP UPF2
Entrez ID		8455	22803
HPRD ID		04388	10309
Ensembl ID		ENSG00000088812	ENSG00000088930
Uniprot IDs		B4DZ36 O75882	Q9H0D6
PDB IDs
Enriched GO Terms of Interacting Partners?		Exosomal Secretion Transcription, DNA-templated Cullin Deneddylation RNA Biosynthetic Process Protein Deneddylation RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Macromolecule Biosynthetic Process DNA Catabolic Process, Exonucleolytic Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression DNA-templated Transcription, Termination Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Phosphodiester Bond Hydrolysis Protein Deubiquitination Protein Modification By Small Protein Removal DNA Catabolic Process Cell Growth	Gene Expression Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Positive Regulation Of Protein Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear MRNA Surveillance Translational Elongation RNA Surveillance Catabolic Process Regulation Of Protein Catabolic Process Translation Cellular Metabolic Process Translational Initiation RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Cellular Macromolecule Catabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Nuclear Export Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Cellular Macromolecule Biosynthetic Process Metabolic Process Estrogen Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Macromolecule Biosynthetic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process RNA Localization Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Wnt Signaling Pathway Ribosome Biogenesis Regulation Of Protein Metabolic Process Cellular Aromatic Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Homocysteine Metabolic Process TRNA Wobble Position Uridine Thiolation Enzyme Active Site Formation Via L-cysteine Persulfide Cellular Response To Phosphate Starvation Negative Regulation Of Potassium Ion Export Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Stability Cellular Protein Metabolic Process Regulation Of Homocysteine Metabolic Process Protein Adenylylation Regulation Of Heart Rate By Hormone
Tagcloud ?		adam17 bnc2 ctsd edar fay ihs klhl7 lsbl lyst mc1r mlph oca2 oprm1 outliers pdia6 pigmentary pigmentation pmel rsb sfs silv statistic sweeps tajima tmem33 trpm1 tyrp1 windows wu	8s arabidopsis at1g52930 at3g15460 atbrx1 biogenesis brx1 bypassed ets eukaryotes export implying intermediates its1 leaves nucleolus orthologs plant pointed processing rbfs ribosomal ribosome rrna spacer steps thaliana transcribed ubiquitously
Tagcloud (Difference) ?		adam17 bnc2 ctsd edar fay ihs klhl7 lsbl lyst mc1r mlph oca2 oprm1 outliers pdia6 pigmentary pigmentation pmel rsb sfs silv statistic sweeps tajima tmem33 trpm1 tyrp1 windows wu	8s arabidopsis at1g52930 at3g15460 atbrx1 biogenesis brx1 bypassed ets eukaryotes export implying intermediates its1 leaves nucleolus orthologs plant pointed processing rbfs ribosomal ribosome rrna spacer steps thaliana transcribed ubiquitously
Tagcloud (Intersection) ?