SNRNP200 and SMNDC1

Number of citations of the paper that reports this interaction (PMID 11331595)
10

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SNRNP200	SMNDC1
Gene Name		small nuclear ribonucleoprotein 200kDa (U5)	survival motor neuron domain containing 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck Intermediate Filament Cytoskeleton
	Molecular Function	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Helicase Activity Identical Protein Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing Apoptotic Process RNA Splicing
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: APC BARD1 BRCA1 CHMP1B ECT2 ERG GRB2 LSM8 MEGF10 PIN1 PRPF8 RNF113A SART1 SF3B2 SMNDC1 SNRNP40 USP19 YWHAB YWHAG	4 interactors: HIST3H3 KPNB1 SNRNP200 SNRPB
Entrez ID		23020	10285
HPRD ID		03391	04627
Ensembl ID		ENSG00000144028
Uniprot IDs		O75643	O75940
PDB IDs		2Q0Z 4F91 4F92 4F93 4KIT	4A4F 4A4H
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Organelle Organization RNA Splicing Regulation Of Cell Cycle MRNA Processing Regulation Of Cell Cycle Process MRNA Metabolic Process Cell Cycle RNA Processing Regulation Of Microtubule Cytoskeleton Organization Apoptotic Process Apoptotic Signaling Pathway Programmed Cell Death Cell Cycle Process Regulation Of Microtubule-based Process Cell Death Death Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Protein K6-linked Ubiquitination Regulation Of Cytoskeleton Organization Regulation Of Phosphorylation Regulation Of Cell Division Regulation Of Cellular Component Organization Cytokinesis Positive Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell Cycle Arrest Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Regulation Of Intracellular Transport Cellular Component Assembly Ribonucleoprotein Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Cellular Response To Organonitrogen Compound Spliceosomal SnRNP Assembly Regulation Of Apoptotic Process Regulation Of Centrosome Duplication	Ribonucleoprotein Complex Assembly Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Biogenesis Ribosomal Protein Import Into Nucleus RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Processing Cellular Nitrogen Compound Metabolic Process MRNA Cis Splicing, Via Spliceosome MRNA Metabolic Process Nitrogen Compound Metabolic Process Apoptotic DNA Fragmentation RNA Processing NLS-bearing Protein Import Into Nucleus Histone MRNA Metabolic Process Cellular Macromolecular Complex Assembly Intracellular Transport Of Virus Protein Import Into Nucleus, Translocation Apoptotic Nuclear Changes Termination Of RNA Polymerase II Transcription Spliceosomal SnRNP Assembly Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Spliceosomal Complex Assembly DNA Metabolic Process DNA-templated Transcription, Termination Execution Phase Of Apoptosis Telomere Maintenance MRNA 3'-end Processing DNA Catabolic Process, Endonucleolytic RNA 3'-end Processing
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