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GNPAT and PEX5
Number of citations of the paper that reports this interaction (PubMedID
22002062
)
71
Data Source:
BioGRID
(affinity chromatography technology, unspecified method, affinity chromatography technology)
GNPAT
PEX5
Description
glyceronephosphate O-acyltransferase
peroxisomal biogenesis factor 5
Image
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Peroxisomal Membrane
Peroxisomal Matrix
Cytosol
Membrane
Cell Junction
Cytoplasm
Mitochondrion
Peroxisome
Peroxisomal Membrane
Peroxisomal Matrix
Golgi Apparatus
Cytosol
Membrane
Protein-containing Complex
Molecular Function
Catalytic Activity
O-acyltransferase Activity
Glycerone-phosphate O-acyltransferase Activity
Transferase Activity
Acyltransferase Activity
Peroxisome Targeting Sequence Binding
Peroxisome Matrix Targeting Signal-1 Binding
Protein Binding
Enzyme Binding
Small GTPase Binding
Peroxisome Membrane Targeting Sequence Binding
Protein Carrier Chaperone
Biological Process
Lipid Metabolic Process
Glycerophospholipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Synapse Assembly
Ether Lipid Biosynthetic Process
Cerebellum Morphogenesis
Paranodal Junction Assembly
Myelination
Membrane Organization
Very Long-chain Fatty Acid Metabolic Process
Pexophagy
Neuron Migration
Protein Monoubiquitination
Protein Targeting To Peroxisome
Lipid Metabolic Process
Fatty Acid Beta-oxidation
Mitochondrion Organization
Mitochondrial Membrane Organization
Endoplasmic Reticulum Organization
Peroxisome Organization
Protein Transport
Protein Import Into Peroxisome Matrix
Protein Import Into Peroxisome Matrix, Docking
Protein Import Into Peroxisome Matrix, Translocation
Protein Import Into Peroxisome Matrix, Receptor Recycling
Cerebral Cortex Cell Migration
Cerebral Cortex Neuron Differentiation
Negative Regulation Of Protein-containing Complex Assembly
Cellular Response To Reactive Oxygen Species
Positive Regulation Of Multicellular Organism Growth
Protein Unfolding
Protein Import Into Peroxisome Matrix, Substrate Release
Protein Import Into Peroxisome Membrane
Cell Development
Neuromuscular Process
Protein Tetramerization
Pathways
Synthesis of PA
Plasmalogen biosynthesis
Peroxisomal protein import
Peroxisomal protein import
Pexophagy
Drugs
Diseases
Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
IgG glycosylation (
23382691
)
Night sleep phenotypes (
27126917
)
Refractive error (
32231278
)
Interacting Genes
6 interacting genes:
AGPS
GPR3
HSPB1
PEX5
RAB35
VDR
77 interacting genes:
ACD
ACOT2
ACOT4
ACOT8
ACOX2
ACOX3
AGXT
AMACR
ANKRD50
ATM
BAAT
BRCA1
CAPRIN2
CCDC14
CROT
DAO
DDO
DECR2
DHRS4
ECI2
EP400P1
EPHX2
GDPD5
GLMN
GNPAT
GSTK1
HACL1
HAO1
HAO2
HMGCL
HNRNPH1
HOXA7
HSPA1A
IDE
IDH1
LDHB
LONP2
MKRN3
MLYCD
MPV17
NOS2
NUDT19
NUDT3
NUDT7
NUFIP2
PAOX
PDZK1
PEX1
PEX10
PEX12
PEX13
PEX14
PEX26
PEX6
PEX7
PIPOX
POT1
PRDX5
PRR13
PSAP
RPL14
S100A6
SCARB1
SCP2
SCRN2
SIRT3
SLC27A2
SNUPN
SSTR5
TIMMDC1
TINF2
TM6SF1
TOMM7
USP2
USP9X
ZFAND3
ZNF772
Entrez ID
8443
5830
HPRD ID
04120
02684
Ensembl ID
ENSG00000116906
ENSG00000139197
Uniprot IDs
O15228
A0A0S2Z480
A0A0S2Z4F3
A0A0S2Z4H1
B4DR50
B4E0T2
P50542
PDB IDs
1FCH
2C0L
2C0M
2J9Q
2W84
3R9A
4BXU
4KXK
4KYO
7Z0K
9GAG
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Multicellular Organismal Process
Negative Regulation Of Protein Kinase C Signaling
Protein Kinase C Inhibitor Activity
Protein Import Into Peroxisome Matrix, Translocation
Peroxisome Membrane Targeting Sequence Binding
Peroxisome
Peroxisome Matrix Targeting Signal-1 Binding
Peroxisomal Matrix
Peroxisome Targeting Sequence Binding
Peroxisomal Membrane
Protein Import Into Peroxisome Matrix, Docking
Negative Regulation Of Phosphate Transmembrane Transport
Calcitriol Binding
Nuclear Receptor-mediated Bile Acid Signaling Pathway
Apoptotic Process Involved In Mammary Gland Involution
Vitamin D Response Element Binding
Bile Acid Nuclear Receptor Activity
Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution
Mammary Gland Branching Involved In Pregnancy
Vitamin D Receptor Signaling Pathway
Lithocholic Acid Binding
Alkylglycerone-phosphate Synthase Activity
Regulation Of Protein Kinase C Signaling
Protein Import Into Peroxisome Membrane
Protein Import Into Peroxisome Matrix, Substrate Release
Positive Regulation Of Vitamin D Receptor Signaling Pathway
Response To Bile Acid
Vitamin D Binding
Positive Regulation Of Apoptotic Process Involved In Morphogenesis
Sphingosine-1-phosphate Receptor Activity
Anterograde Axonal Protein Transport
Protein Targeting To Peroxisome
Protein Import Into Peroxisome Matrix, Receptor Recycling
Protein Carrier Chaperone
Positive Regulation Of Apoptotic Process Involved In Development
Regulation Of Vitamin D Receptor Signaling Pathway
Regulation Of Phosphate Transport
Plasma Membrane To Endosome Transport
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Endothelial Cell Chemotaxis
Protein Transport
Protein Transport Along Microtubule
Response To Growth Factor
Contractile Muscle Fiber
Protein Unfolding
Protein Import Into Peroxisome Matrix
Phosphate Ion Transmembrane Transport
Ether Lipid Biosynthetic Process
Protein Localization To Endosome
Cell Projection Membrane
Peroxisome
Peroxisomal Matrix
Carboxylic Acid Catabolic Process
Establishment Of Protein Localization To Peroxisome
Protein Import Into Peroxisome Matrix
Fatty Acid Oxidation
Carboxylic Acid Metabolic Process
Fatty Acid Catabolic Process
Organic Acid Metabolic Process
Lipid Oxidation
Peroxisome Organization
Fatty Acid Metabolic Process
Monocarboxylic Acid Metabolic Process
Peroxisomal Membrane Transport
Peroxisomal Membrane
Lipid Modification
Protein Import Into Peroxisome Matrix, Receptor Recycling
Intracellular Protein Transmembrane Transport
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Small Molecule Metabolic Process
Lipid Metabolic Process
Protein Unfolding
Lipid Catabolic Process
Protein Transmembrane Transport
Catabolic Process
Fatty Acid Beta-oxidation
Receptor Recycling
Protein Targeting To Peroxisome
Cytosol
Establishment Of Protein Localization To Organelle
Receptor Metabolic Process
Sulfur Compound Metabolic Process
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Carboxylic Acid Biosynthetic Process
Protein Import Into Peroxisome Matrix, Substrate Release
Bile Acid Metabolic Process
Fatty Acid Alpha-oxidation
Oxidoreductase Activity
Protein Localization To Organelle
Purine-containing Compound Metabolic Process
Small Molecule Biosynthetic Process
Peroxisomal Importomer Complex
Malonyl-CoA Catabolic Process
Protein Transmembrane Transporter Activity
Nucleoside Phosphate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Protein Import Into Peroxisome Matrix, Translocation
Telomere Assembly
Organophosphate Metabolic Process
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