OIP5 and MYRIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OIP5	MYRIP
Description		Opa interacting protein 5	myosin VIIA and Rab interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Chromocenter Cajal Body Nuclear Speck CENP-A Recruiting Complex	Exocyst Photoreceptor Outer Segment Cytoplasm Cytosol Actin Cytoskeleton Transport Vesicle Cortical Actin Cytoskeleton Dense Core Granule Cytoplasmic Vesicle Melanosome Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Actin Binding Protein Binding Zinc Ion Binding Myosin Binding Small GTPase Binding Metal Ion Binding Protein Kinase A Binding
	Biological Process	Chromosome Segregation Cell Communication CENP-A Containing Chromatin Assembly Cell Division Pericentric Heterochromatin Organization	Intracellular Protein Transport Positive Regulation Of Insulin Secretion
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	Insulin processing Regulation of MITF-M-dependent genes involved in pigmentation
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Ulcerative colitis ( 28067908)	Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Rapid automised naming of letters ( 30741946) Sleep-related phenotypes ( 17903308) Whole brain grey matter density ( 31530798)
Interacting Genes		142 interacting genes: A1CF ABI2 ABI3 ABL2 AGXT BCAS2 BEX2 BFSP2 BLOC1S5 BRAF C1orf94 C21orf91 C7orf57 CASP10 CBY2 CCDC22 CCDC24 CCHCR1 CDR2L CEP57 CERK CHCHD2 CIMIP1 COX5B CRACR2A CTNNA3 DMRT3 DTNBP1 DTX2 DUSP21 EFHC1 EIF4ENIF1 ESS2 FAM161B FAM222B FOXJ1 FSD2 GADD45GIP1 GCC1 GEM GLIS2 GPANK1 GPS2 HAPLN2 HGS HJURP HOXB5 HOXB9 HOXC8 HSF4 IL16 KANK2 KDM1A KIF9 KLHL38 KLHL42 KNSTRN KRT14 KRT15 KRT27 KRT3 KRT35 KRT37 KRT40 KRT6B KRT75 KRT81 KRT83 KRT86 KRTAP13-2 KRTAP19-5 KRTAP19-6 LENG1 MECOM MED4 MEIS2 MGAT5B MIIP MIS18A MIS18BP1 MISP MORN3 MYEF2 MYRIP NDUFAB1 NECAB2 NUP54 NUP62 P4HA3 PATZ1 PEX19 PHETA1 PITX2 PLAGL2 POLR2J POU6F2 PRR35 PSMB1 RAB26 RABGEF1 RAF1 RARG RIBC1 RUNX1T1 RUSC1 S100Z SAMD7 SAXO1 SAXO4 SHISA6 SKIL SMARCE1 SNRNP25 SNRPB SOHLH1 SORBS3 SPATA24 SPMIP4 SYCE1L TEKT3 TEX12 TFAP2D TFIP11 TIMM8A TLX3 TMPO TPM3 TPRX1 TRIB3 TRIM73 TRIP6 TROAP TSSK3 USHBP1 USP2 USP54 WASHC1 YTHDF1 ZIC1 ZMAT1 ZNF417 ZNF655	6 interacting genes: C1orf216 MYO7A OIP5 RAB27A RAB27B VPS26C
Entrez ID		11339	25924
HPRD ID		09352	14796
Ensembl ID		ENSG00000104147	ENSG00000170011
Uniprot IDs		O43482	Q8NFW9
PDB IDs		7SFY
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Keratin Filament Protein Binding Supramolecular Fiber Organization Cytoskeleton Axonemal A Tubule Inner Sheath Cytoskeleton Organization Structural Molecule Activity Organelle Organization Sperm Flagellum Keratinization Motile Cilium CENP-A Containing Chromatin Assembly Pericentric Heterochromatin Organization CENP-A Recruiting Complex	Melanosome Pigment Granule Localization Protein Domain Specific Binding Pigment Granule Transport Multivesicular Body Membrane Exocytic Vesicle Myosin V Binding Multivesicular Body Sorting Pathway Apical Plasma Membrane Vesicle-mediated Transport Upper Tip-link Density Protein Transport Myosin VII Complex Photoreceptor Outer Segment GDP Binding Positive Regulation Of Exocytosis Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway G Protein Activity Establishment Of Protein Localization Intracellular Protein Transport Establishment Of Vesicle Localization Secretory Granule Vesicle Localization Establishment Of Localization In Cell Complement-dependent Cytotoxicity Pericentric Heterochromatin Organization CENP-A Recruiting Complex Late Endosome Phagolysosome Assembly Stereocilium Base Intracellular Protein Localization Exosomal Secretion Endosome Equilibrioception Regulation Of Exocytosis Weibel-Palade Body Exocytosis Platelet Dense Granule Membrane Natural Killer Cell Degranulation Photoreceptor Cell Cilium Anterograde Axonal Protein Transport Establishment Of Organelle Localization CENP-A Containing Chromatin Assembly Chromocenter Positive Regulation Of Secretion By Cell Protein Transport Along Microtubule Vesicle Organization GTPase Activity Positive Regulation Of Secretion
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