OIP5 and MYEF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OIP5	MYEF2
Description		Opa interacting protein 5	myelin expression factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Chromocenter Cajal Body Nuclear Speck CENP-A Recruiting Complex	Nucleus
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Chromosome Segregation Cell Communication CENP-A Containing Chromatin Assembly Cell Division Pericentric Heterochromatin Organization	Myotube Differentiation Neuron Differentiation
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Ulcerative colitis ( 28067908)	Skin pigmentation ( 28300201)
Interacting Genes		142 interacting genes: A1CF ABI2 ABI3 ABL2 AGXT BCAS2 BEX2 BFSP2 BLOC1S5 BRAF C1orf94 C21orf91 C7orf57 CASP10 CBY2 CCDC22 CCDC24 CCHCR1 CDR2L CEP57 CERK CHCHD2 CIMIP1 COX5B CRACR2A CTNNA3 DMRT3 DTNBP1 DTX2 DUSP21 EFHC1 EIF4ENIF1 ESS2 FAM161B FAM222B FOXJ1 FSD2 GADD45GIP1 GCC1 GEM GLIS2 GPANK1 GPS2 HAPLN2 HGS HJURP HOXB5 HOXB9 HOXC8 HSF4 IL16 KANK2 KDM1A KIF9 KLHL38 KLHL42 KNSTRN KRT14 KRT15 KRT27 KRT3 KRT35 KRT37 KRT40 KRT6B KRT75 KRT81 KRT83 KRT86 KRTAP13-2 KRTAP19-5 KRTAP19-6 LENG1 MECOM MED4 MEIS2 MGAT5B MIIP MIS18A MIS18BP1 MISP MORN3 MYEF2 MYRIP NDUFAB1 NECAB2 NUP54 NUP62 P4HA3 PATZ1 PEX19 PHETA1 PITX2 PLAGL2 POLR2J POU6F2 PRR35 PSMB1 RAB26 RABGEF1 RAF1 RARG RIBC1 RUNX1T1 RUSC1 S100Z SAMD7 SAXO1 SAXO4 SHISA6 SKIL SMARCE1 SNRNP25 SNRPB SOHLH1 SORBS3 SPATA24 SPMIP4 SYCE1L TEKT3 TEX12 TFAP2D TFIP11 TIMM8A TLX3 TMPO TPM3 TPRX1 TRIB3 TRIM73 TRIP6 TROAP TSSK3 USHBP1 USP2 USP54 WASHC1 YTHDF1 ZIC1 ZMAT1 ZNF417 ZNF655	41 interacting genes: COG8 GOLGA2 LNX1 MIR128-2 MIR141 MIR15A MIR17 MIR19B1 MIR19B2 MIR200A MIR20A MIR20B MIR21 MIR221 MIR25 MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR9-1 MIR9-2 MIR93 MIRLET7A3 MIRLET7B MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NFKBID OGT OIP5 PLEKHG4 TEX11 TRAF1 TRIM23 ZRANB1
Entrez ID		11339	50804
HPRD ID		09352	14794
Ensembl ID		ENSG00000104147	ENSG00000104177
Uniprot IDs		O43482	A0A0A0MQW0 Q9P2K5
PDB IDs		7SFY
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Keratin Filament Protein Binding Supramolecular Fiber Organization Cytoskeleton Axonemal A Tubule Inner Sheath Cytoskeleton Organization Structural Molecule Activity Organelle Organization Sperm Flagellum Keratinization Motile Cilium CENP-A Containing Chromatin Assembly Pericentric Heterochromatin Organization CENP-A Recruiting Complex	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Extracellular Vesicle MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Translation Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA Destabilization RNA Destabilization Regulation Of Gene Expression Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Macromolecule Metabolic Process Extracellular Space Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Vasculature Development Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Developmental Process Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Anatomical Structure Morphogenesis
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