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ASCC2 and ASS1
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ASCC2
ASS1
Description
activating signal cointegrator 1 complex subunit 2
argininosuccinate synthase 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nuclear Speck
Cytosolic Ribosome
RQC-trigger Complex
DNA Repair Complex
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Neuronal Cell Body
Perikaryon
Extracellular Exosome
Cell Body Fiber
Molecular Function
Protein Binding
Ubiquitin Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Nucleotide Binding
RNA Binding
Argininosuccinate Synthase Activity
Protein Binding
ATP Binding
Toxic Substance Binding
Amino Acid Binding
Ligase Activity
Identical Protein Binding
Biological Process
DNA Replication
DNA Repair
DNA Alkylation Repair
Regulation Of DNA-templated Transcription
DNA Damage Response
Ribosome Disassembly
Rescue Of Stalled Ribosome
Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Urea Cycle
Citrulline Metabolic Process
Argininosuccinate Metabolic Process
Kidney Development
Liver Development
L-arginine Biosynthetic Process
Aspartate Metabolic Process
Acute-phase Response
Midgut Development
Response To Nutrient
Circadian Rhythm
Amino Acid Biosynthetic Process
Response To Xenobiotic Stimulus
Response To Toxic Substance
Response To Zinc Ion
Response To Mycotoxin
Response To Amine
Response To Estradiol
Response To Lipopolysaccharide
Response To Amino Acid
Response To Peptide Hormone
Positive Regulation Of Nitric Oxide Biosynthetic Process
Response To Steroid Hormone
Response To Glucocorticoid
Response To Growth Hormone
Diaphragm Development
Response To Fatty Acid
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Ammonium Ion
Cellular Response To CAMP
Cellular Response To Type II Interferon
Cellular Response To Tumor Necrosis Factor
Cellular Response To Glucagon Stimulus
Cellular Response To Oleic Acid
Cellular Response To Amine Stimulus
Cellular Response To Laminar Fluid Shear Stress
Cellular Response To Dexamethasone Stimulus
Negative Regulation Of Leukocyte Cell-cell Adhesion
Pathways
ALKBH3 mediated reversal of alkylation damage
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Urea cycle
Drugs
Arginine
Aspartic acid
Aspartic acid
Citrulline
Citrulline
ATP
Diseases
Citrullinemia (CTLN)
GWAS
Bipolar disorder or attention deficit hyperactivity disorder (
27890468
)
Crohn's disease (
28067908
)
Hemoglobin levels (
32327693
)
IgA levels (
28628107
)
Immature fraction of reticulocytes (
27863252
)
Inflammatory bowel disease (
28067908
)
Mean corpuscular hemoglobin concentration (
32888494
)
Refractive error (
32231278
)
Spleen volume (
34128465
)
Telomere length (
24478790
)
Tonsillectomy (
27941131
)
Type 2 diabetes (
30297969
)
Type 2 diabetes (adjusted for BMI) (
29632382
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Interacting Genes
41 interacting genes:
ASS1
CKAP4
CUTC
DEAF1
EEF1D
ELAC2
FAF1
FBP1
FUNDC2
GADD45A
GFER
GNL3
GTF3C1
IGSF9
IMMT
KATNAL1
KDM1A
LPL
MAP3K1
MED31
MYH9
OLA1
PCBD2
PIK3CD
PIN4
PJA1
POLA2
POLDIP2
PRPF18
RADIL
RNF11
RPA1
RPLP1
SASH1
SMURF1
SNRPB
SNW1
TBC1D17
TRIP4
UBC
URM1
15 interacting genes:
AKTIP
APP
ARAF
ASCC2
ELN
JAK2
LINC01554
MLH1
MT2A
PTPN1
SLC13A1
SUMO2
TERF1
TERF2
USP4
Entrez ID
84164
445
HPRD ID
16515
04590
Ensembl ID
ENSG00000100325
ENSG00000130707
Uniprot IDs
Q9H1I8
P00966
Q5T6L4
PDB IDs
2DI0
6YXQ
2NZ2
Enriched GO Terms of Interacting Partners
?
Macromolecule Metabolic Process
Nucleoplasm
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Endosome Lumen
Negative Regulation Of Mitotic Recombination
Cellular Response To Interleukin-3
Regulation Of Mitotic Recombination
Telomerase Activity
Shelterin Complex
Signaling Receptor Activator Activity
Meiotic Telomere Clustering
Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Telomere Localization
Nuclear Telomere Cap Complex
Telomeric D-loop Disassembly
Double-stranded Telomeric DNA Binding
G-rich Strand Telomeric DNA Binding
Telomeric Loop Disassembly
Telomere Capping
Acetylcholine Receptor Binding
Postsynapse
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Protein Metabolic Process
Intracellular Copper Ion Homeostasis
Regulation Of Establishment Of Protein Localization
Copper Ion Homeostasis
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Phosphorus Metabolic Process
Insulin Receptor Binding
Cellular Response To Copper Ion
Positive Regulation Of Phosphate Metabolic Process
Growth Hormone Receptor Signaling Pathway
RNA-templated DNA Biosynthetic Process
Negative Regulation Of DNA Metabolic Process
Ephrin Receptor Binding
Telomeric DNA Binding
Positive Regulation Of Macromolecule Metabolic Process
Microglial Cell Activation
Regulation Of Protein Modification Process
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Amyloid-beta Complex
Positive Regulation Of Metabolic Process
Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Growth Cone Lamellipodium
Positive Regulation Of Nitric Oxide Biosynthetic Process
Response To Copper Ion
Enzyme Binding
Regulation Of Response To Calcium Ion
Response To Nerve Growth Factor
Cell Activation Involved In Immune Response
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Tagcloud (Intersection)
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