ASCC2 and CUTC

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	CUTC
Gene Name		activating signal cointegrator 1 complex subunit 2	cutC copper transporter
Image
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function		Copper Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Copper Ion Transport Protein Tetramerization Copper Ion Homeostasis
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 22412388) Obesity-related traits ( 23251661)
Protein-Protein Interactions		38 interactors: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT JUN KDM1A LPL MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RELA RNF11 RPA1 RPLP1 SNRPB SNW1 SRF TBC1D17 TRIP4 URM1	11 interactors: ASCC2 BCL6 CEP76 LNX1 NADSYN1 NIF3L1 NUDT18 PIM2 SDCBP SLC27A6 SPG21
Entrez ID		84164	51076
HPRD ID		16515	13100
Ensembl ID		ENSG00000100325	ENSG00000119929
Uniprot IDs		Q9H1I8	Q9NTM9
PDB IDs		2DI0	3IWP
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Myeloid Leukocyte Differentiation RNA Metabolic Process Nitrogen Compound Metabolic Process Myeloid Cell Differentiation Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation By Host Of Viral Transcription Leukocyte Differentiation RNA Biosynthetic Process Metabolic Process Response To Abiotic Stimulus Mitochondrion Organization Hemopoiesis Monocyte Differentiation Transcription, DNA-templated Telomere Maintenance Via Semi-conservative Replication Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Platelet Formation Protein Tetramerization Response To Radiation Platelet Morphogenesis Immune System Development Macromolecule Biosynthetic Process Telomere Maintenance Via Recombination Regulation Of Histone H3-K4 Methylation Nuclear DNA Replication Positive Regulation Of Transcription, DNA-templated Response To CAMP Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Response To Drug DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Response To Stress Gene Expression Blood Vessel Endothelial Cell Migration Interaction With Symbiont Learning Membrane Protein Proteolysis Aging Regulation Of Cell Proliferation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organophosphorus Positive Regulation Of Macromolecule Biosynthetic Process	GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Negative Regulation Of Mast Cell Cytokine Production Negative Regulation Of Isotype Switching To IgE Isotypes Dihydrobiopterin Metabolic Process Negative Regulation Of T-helper 2 Cell Differentiation Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process
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