ASCC2 and GFER

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	GFER
Gene Name		activating signal cointegrator 1 complex subunit 2	growth factor, augmenter of liver regeneration
Image
Gene Ontology Annotations	Cellular Component		Extracellular Region Cytoplasm Mitochondrion Mitochondrial Intermembrane Space
	Molecular Function		Protein Binding Growth Factor Activity Protein Disulfide Oxidoreductase Activity Thiol Oxidase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Oxidation-reduction Process
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT JUN KDM1A LPL MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RELA RNF11 RPA1 RPLP1 SNRPB SNW1 SRF TBC1D17 TRIP4 URM1	7 interactors: ASCC2 BNIPL COPS2 COPS5 PLEKHF2 SMAD2 TXN
Entrez ID		84164	2671
HPRD ID		16515	02954
Ensembl ID		ENSG00000100325	ENSG00000127554
Uniprot IDs		Q9H1I8	P55789
PDB IDs		2DI0	3MBG 3O55 3TK0 3U2L 3U2M 3U5S
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Myeloid Leukocyte Differentiation RNA Metabolic Process Nitrogen Compound Metabolic Process Myeloid Cell Differentiation Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation By Host Of Viral Transcription Leukocyte Differentiation RNA Biosynthetic Process Metabolic Process Response To Abiotic Stimulus Mitochondrion Organization Hemopoiesis Monocyte Differentiation Transcription, DNA-templated Telomere Maintenance Via Semi-conservative Replication Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Platelet Formation Protein Tetramerization Response To Radiation Platelet Morphogenesis Immune System Development Macromolecule Biosynthetic Process Telomere Maintenance Via Recombination Regulation Of Histone H3-K4 Methylation Nuclear DNA Replication Positive Regulation Of Transcription, DNA-templated Response To CAMP Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Response To Drug DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Response To Stress Gene Expression Blood Vessel Endothelial Cell Migration Interaction With Symbiont Learning Membrane Protein Proteolysis Aging Regulation Of Cell Proliferation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organophosphorus Positive Regulation Of Macromolecule Biosynthetic Process	Cullin Deneddylation Protein Deneddylation Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Removal Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry RNA Metabolic Process Regulation Of Growth Rate Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Exosomal Secretion Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Primary MiRNA Processing Negative Regulation Of Protein Export From Nucleus Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Binding Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death SMAD Protein Complex Assembly Nucleobase-containing Compound Metabolic Process Regulation Of Hydrogen Peroxide-induced Cell Death Paraxial Mesoderm Morphogenesis Nodal Signaling Pathway Nucleobase-containing Small Molecule Interconversion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis Foregut Morphogenesis
Tagcloud ?			acting alr apoptotic augmenter behaviour caspase clusterin complementary encodes erv1 glioma hepatectomized integrity lethal modulates named neuroblastoma normoxic oxidase peroxide preserve ralr regenerating regeneration ros shed sulfhydryl supports t98g
Tagcloud (Difference) ?			acting alr apoptotic augmenter behaviour caspase clusterin complementary encodes erv1 glioma hepatectomized integrity lethal modulates named neuroblastoma normoxic oxidase peroxide preserve ralr regenerating regeneration ros shed sulfhydryl supports t98g
Tagcloud (Intersection) ?