CTTNBP2 and CTTN

Number of citations of the paper that reports this interaction (PMID 9813110)
18

Data Source:
HPRD (in vitro)

		CTTNBP2	CTTN
Gene Name		cortactin binding protein 2	cortactin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Cortex Synaptic Vesicle Dendritic Spine	Ruffle Cytoplasm Cytoskeleton Actin Filament Coated Pit Focal Adhesion Cell Cortex Voltage-gated Potassium Channel Complex Lamellipodium Growth Cone Cortical Cytoskeleton Dendritic Spine Extracellular Vesicular Exosome Mitotic Spindle Midzone
	Molecular Function	SH3 Domain Binding	Protein Binding
	Biological Process	Brain Development	Intracellular Protein Transport Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Actin Filament Polymerization Regulation Of Axon Extension Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Dendritic Spine Maintenance Lamellipodium Organization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: CTTN	36 interactors: ACD ACTA1 ACTG1 ACTR2 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 CASP3 CD2AP CHD3 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 FER FGD1 GRB2 HAX1 HDAC6 HIP1R KCNA2 MET MYLK SDC3 SHANK2 SIRT1 SPRR2A SRC SYK TINF2 TJP1 TNK2 WASL WIPF1
Entrez ID		83992	2017
HPRD ID		09890	01268
Ensembl ID		ENSG00000077063	ENSG00000085733
Uniprot IDs		Q20BG9 Q8WZ74	Q14247 Q53HG7
PDB IDs			1X69 2D1X
Enriched GO Terms of Interacting Partners?		Dendritic Spine Maintenance Substrate-dependent Cell Migration, Cell Extension Dendritic Spine Organization Cellular Component Maintenance Focal Adhesion Assembly Substrate-dependent Cell Migration Actin Filament Polymerization Adherens Junction Assembly Cell-substrate Junction Assembly Lamellipodium Organization Actin Cytoskeleton Reorganization Regulation Of Axon Extension Actin Polymerization Or Depolymerization Adherens Junction Organization Protein Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Size Regulation Of Axonogenesis Cell-matrix Adhesion Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Junction Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cell-cell Junction Organization Cell-substrate Adhesion Negative Regulation Of Apoptotic Signaling Pathway Cell Projection Assembly Regulation Of Developmental Growth Actin Filament Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Cellular Protein Complex Assembly Regulation Of Cell Growth Receptor-mediated Endocytosis Regulation Of Actin Cytoskeleton Organization Regulation Of Neuron Projection Development Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Endocytosis Fc Receptor Signaling Pathway Cellular Response To Stimulus Cellular Component Assembly Regulation Of Cellular Component Organization Actin Cytoskeleton Organization Actin Filament-based Process Anatomical Structure Development Response To External Stimulus Developmental Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Phagocytosis Cell Communication Positive Regulation Of Organelle Organization Multicellular Organismal Development Immune Response-activating Cell Surface Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Organelle Organization Movement Of Cell Or Subcellular Component Chemotaxis Immune Response-regulating Signaling Pathway System Development Signaling Cytoskeleton Organization Signal Transduction Positive Regulation Of Immune System Process Response To Stimulus Cell Projection Organization Cell Morphogenesis Involved In Differentiation Axon Guidance Locomotion Innate Immune Response Positive Regulation Of Protein Complex Assembly Regulation Of Immune System Process Cell Morphogenesis Actin Filament Organization Positive Regulation Of Immune Response Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Regulation Of Immune Response Peptidyl-tyrosine Autophosphorylation Regulation Of Protein Complex Assembly Positive Regulation Of Cytoskeleton Organization
Tagcloud ?		3c anticipate asz1 away bait cftr conductance constructs cooperatively correspond cystic depend designing dnase enable encompasses flanking governing hypersensitive intergenic intronic introns kb locus looped lying modify recruit transgenes	applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1
Tagcloud (Difference) ?		3c anticipate asz1 away bait cftr conductance constructs cooperatively correspond cystic depend designing dnase enable encompasses flanking governing hypersensitive intergenic intronic introns kb locus looped lying modify recruit transgenes	applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1
Tagcloud (Intersection) ?