RBM4B and POLR2M

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM4B	POLR2M
Gene Name		RNA binding motif protein 4B	polymerase (RNA) II (DNA directed) polypeptide M
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Gene Ontology Annotations	Cellular Component	Nucleolus	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	Nucleotide Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding	DNA-directed RNA Polymerase Activity
	Biological Process	MRNA Processing Regulation Of Translation Circadian Rhythm RNA Splicing Positive Regulation Of Gene Expression Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod	RNA Biosynthetic Process Maintenance Of ER Location
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		8 interactors: APC APP DZIP3 HNRNPM HNRNPUL1 MRPS9 POLR2M SMYD1	19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		83759	81488
HPRD ID		15230	07575
Ensembl ID		ENSG00000173914	ENSG00000255529
Uniprot IDs		E9PLB0 Q9BQ04	P0CAP1 P0CAP2 Q6EEV4
PDB IDs		2DGT	2KXS
Enriched GO Terms of Interacting Partners?		MRNA Processing Maintenance Of ER Location MRNA Metabolic Process RNA Processing Synaptic Growth At Neuromuscular Junction Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Collateral Sprouting In Absence Of Injury Endoplasmic Reticulum Localization Cellular Metabolic Process Negative Regulation Of Odontogenesis Collateral Sprouting Axon Midline Choice Point Recognition RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Metaphase/anaphase Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition MRNA Splicing, Via Spliceosome Gene Expression RNA Splicing, Via Transesterification Reactions Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Cell Cycle Phase Transition DNA Damage Response, Detection Of DNA Damage Neuron Remodeling	Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process
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