RBM4B and SMYD1

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RBM4B	SMYD1
Gene Name		RNA binding motif protein 4B	SET and MYND domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus	Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process	MRNA Processing Regulation Of Translation Circadian Rhythm RNA Splicing Positive Regulation Of Gene Expression Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod	Chromatin Remodeling Transcription, DNA-templated Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		8 interactors: APC APP DZIP3 HNRNPM HNRNPUL1 MRPS9 POLR2M SMYD1	19 interactors: ADSS BHLHE40 C11orf16 C11orf53 CCDC113 FAM204A H3F3C HDAC2 HDAC3 HOMEZ LENG8 MYH7B NACA OGDHL RBM4B TTC33 UTP14A WDR77 ZBTB44
Entrez ID		83759	150572
HPRD ID		15230	06025
Ensembl ID		ENSG00000173914	ENSG00000115593
Uniprot IDs		E9PLB0 Q9BQ04	E9PHG3 Q5HYE8 Q8NB12
PDB IDs		2DGT
Enriched GO Terms of Interacting Partners?		MRNA Processing Maintenance Of ER Location MRNA Metabolic Process RNA Processing Synaptic Growth At Neuromuscular Junction Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Collateral Sprouting In Absence Of Injury Endoplasmic Reticulum Localization Cellular Metabolic Process Negative Regulation Of Odontogenesis Collateral Sprouting Axon Midline Choice Point Recognition RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Metaphase/anaphase Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition MRNA Splicing, Via Spliceosome Gene Expression RNA Splicing, Via Transesterification Reactions Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Cell Cycle Phase Transition DNA Damage Response, Detection Of DNA Damage Neuron Remodeling	Circadian Regulation Of Gene Expression Circadian Rhythm RNA Metabolic Process Rhythmic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone H4 Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Histone H3 Deacetylation Nitrogen Compound Metabolic Process Histone H3-K9 Modification Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Histone Deacetylation Regulation Of Developmental Growth Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Response To Ammonium Ion Regulation Of Striated Muscle Cell Differentiation RNA Biosynthetic Process Regulation Of Circadian Rhythm Maintenance Of Chromatin Silencing 'de Novo' AMP Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression Response To Abiotic Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development AMP Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Regulation Of Muscle Cell Differentiation Aspartate Metabolic Process Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Morphogenesis
Tagcloud ?			adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Difference) ?			adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Intersection) ?