RBM4B and MIRLET7G

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		RBM4B	MIRLET7G
Description		RNA binding motif protein 4B	microRNA let-7g
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Speck Protein-containing Complex	Extracellular Space RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of Translation Circadian Rhythm RNA Splicing Positive Regulation Of Gene Expression Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod	Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Negative Regulation Of SMAD Protein Signal Transduction Cellular Response To Glucose Stimulus Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 23974872)
Interacting Genes		22 interacting genes: APC APP ATN1 DZIP3 HNRNPM HNRNPUL1 KLF1 MIR21 MIR214 MIR34B MIR9-2 MIRLET7B MIRLET7C MIRLET7D MIRLET7G MIRLET7I MRPS9 NFKBID POLR2M SMYD1 SNRPA TSGA10IP	116 interacting genes: ADARB1 APOBEC3B AQR ATXN2L C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PAXBP1 PDCD11 PLOD1 PLRG1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RBM4B RBM5 RBM6 RBMS1 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SF3B5 SFPQ SPOUT1 STRBP SUGP1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR
Entrez ID		83759	406890
HPRD ID		15230
Ensembl ID		ENSG00000173914	ENSG00000199150
Uniprot IDs		E9PLB0 Q9BQ04
PDB IDs		2DGT
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Gene Expression Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Smooth Muscle Cell Migration Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Cardiac Muscle Hypertrophy MRNA 3'-UTR Binding Positive Regulation Of MRNA Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Positive Regulation Of Catabolic Process Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Connective Tissue Replacement Positive Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of MRNA Stability Regulation Of Cardiac Muscle Hypertrophy Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of RNA Stability Regulation Of Connective Tissue Replacement Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Negative Regulation Of Signal Transduction Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Tissue Remodeling Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Gene Expression Alternative MRNA Splicing, Via Spliceosome Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Macromolecule Metabolic Process Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of T-helper Cell Differentiation	RNA Binding RNA Processing Nucleic Acid Binding RNA Metabolic Process MRNA Processing MRNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Macromolecule Metabolic Process Regulation Of RNA Splicing Nucleoplasm Regulation Of MRNA Metabolic Process Nucleus Catalytic Step 2 Spliceosome Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Regulation Of Translation MRNA 3'-UTR Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of RNA Stability Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of MRNA Catabolic Process U2 SnRNP RNA Stabilization MRNA Stabilization Negative Regulation Of Translation Regulation Of Metabolic Process MiRNA Processing Protein-RNA Complex Assembly TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity U2-type Prespliceosome Assembly Negative Regulation Of Macromolecule Metabolic Process
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