RBM4B and MIR34B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		RBM4B	MIR34B
Description		RNA binding motif protein 4B	microRNA 34b
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Speck Protein-containing Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of Translation Circadian Rhythm RNA Splicing Positive Regulation Of Gene Expression Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod	Negative Regulation Of Cell Population Proliferation MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756)
Interacting Genes		22 interacting genes: APC APP ATN1 DZIP3 HNRNPM HNRNPUL1 KLF1 MIR21 MIR214 MIR34B MIR9-2 MIRLET7B MIRLET7C MIRLET7D MIRLET7G MIRLET7I MRPS9 NFKBID POLR2M SMYD1 SNRPA TSGA10IP	109 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2 ATXN2L C1QBP CDC5L CELF1 CELF2 CPSF1 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MTERF3 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PIP5K1A PLOD1 PTBP1 PTBP3 PTCD3 PUF60 PURA PURB QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBM45 RBM4B RTCA RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM56 U2SURP UPF1 USP36 UTP20 WDR33 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		83759	407041
HPRD ID		15230
Ensembl ID		ENSG00000173914	ENSG00000207811
Uniprot IDs		E9PLB0 Q9BQ04
PDB IDs		2DGT
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Gene Expression Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Smooth Muscle Cell Migration Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Cardiac Muscle Hypertrophy MRNA 3'-UTR Binding Positive Regulation Of MRNA Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Positive Regulation Of Catabolic Process Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Connective Tissue Replacement Positive Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of MRNA Stability Regulation Of Cardiac Muscle Hypertrophy Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of RNA Stability Regulation Of Connective Tissue Replacement Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Negative Regulation Of Signal Transduction Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Tissue Remodeling Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Gene Expression Alternative MRNA Splicing, Via Spliceosome Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Macromolecule Metabolic Process Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of T-helper Cell Differentiation	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Splicing, Via Transesterification Reactions Nucleus Regulation Of MRNA Metabolic Process Nucleoplasm Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Ribonucleoprotein Complex Catalytic Step 2 Spliceosome Spliceosomal Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translation Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding MiRNA Binding Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process RNA Stabilization TRNA Aminoacylation MRNA Stabilization Regulation Of Primary Metabolic Process Regulation Of RNA Stability RNA Transport Regulation Of MRNA Stability U2 SnRNP Positive Regulation Of Gene Expression Regulation Of Metabolic Process Ligase Activity Protein-RNA Complex Assembly
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