SMYD1 and SNX11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMYD1	SNX11
Description		SET and MYND domain containing 1	sorting nexin 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Endosome Plasma Membrane Membrane
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K4 Trimethyltransferase Activity	Protein Binding Lipid Binding Phosphatidylinositol Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of DNA-templated Transcription	Intracellular Protein Transport Protein Transport Vesicle Organization
Pathways		Cardiogenesis
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)	Appendicular lean mass ( 33097823) Body mass index ( 26426971) Generalized epilepsy ( 22949513) Triglyceride levels ( 32154731 32203549)
Interacting Genes		45 interacting genes: ARID5A BACH2 BHLHE40 C11orf16 CCDC33 CFAP263 CFAP68 CFTR CIMIP2A DISC1 DVL1 FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU2AF2 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44	10 interacting genes: ARL6IP1 MAJIN NECAB1 RABAC1 REEP6 RPRM SMYD1 SMYD2 YIF1A ZMYND10
Entrez ID		150572	29916
HPRD ID		06025	15410
Ensembl ID		ENSG00000115593	ENSG00000002919
Uniprot IDs		E9PHG3 Q8NB12	Q9Y5W9
PDB IDs			4IKB 4IKD 6KOI 6KOJ 6KOK
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Protein Decrotonylase Activity Histone Decrotonylase Activity Protein De-2-hydroxyisobutyrylase Activity Protein Lysine Delactylase Activity Axonemal A Tubule Inner Sheath Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Deacetylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Sperm Flagellum Cilium Movement Involved In Cell Motility Circadian Rhythm Protein Lysine Deacetylase Activity Microtubule-based Movement	Histone H3K4 Trimethyltransferase Activity Endoplasmic Reticulum Organization Positive Regulation Of Motile Cilium Assembly
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