SMYD1 and ZBTB44

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SMYD1	ZBTB44
Description		SET and MYND domain containing 1	zinc finger and BTB domain containing 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K4 Trimethyltransferase Activity	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of DNA-templated Transcription
Pathways		Cardiogenesis
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)	Diastolic blood pressure ( 27841878) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		45 interacting genes: ARID5A BACH2 BHLHE40 C11orf16 CCDC33 CFAP263 CFAP68 CFTR CIMIP2A DISC1 DVL1 FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU2AF2 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44	18 interacting genes: AP1M1 ENO1 ERG ETS2 FAM124A FBXO7 GLRX3 HUNK POLI PSMA6 RAD23A RSPH1 SMAD1 SMAD7 SMURF2 SMYD1 TIAM1 WDFY3
Entrez ID		150572	29068
HPRD ID		06025	13692
Ensembl ID		ENSG00000115593	ENSG00000196323
Uniprot IDs		E9PHG3 Q8NB12	H0YEM9 Q8NCP5
PDB IDs
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Protein Decrotonylase Activity Histone Decrotonylase Activity Protein De-2-hydroxyisobutyrylase Activity Protein Lysine Delactylase Activity Axonemal A Tubule Inner Sheath Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Deacetylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Sperm Flagellum Cilium Movement Involved In Cell Motility Circadian Rhythm Protein Lysine Deacetylase Activity Microtubule-based Movement	Cytosol Cell Fate Commitment Involved In Formation Of Primary Germ Layer Heteromeric SMAD Protein Complex I-SMAD Binding Positive Regulation Of Proteolysis Transcription Corepressor Activity Nucleus Ureteric Bud Development SMAD Protein Signal Transduction Mesonephric Epithelium Development Positive Regulation Of Cartilage Development Mesonephric Tubule Development Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Purine Ribonucleoside Triphosphate Binding Wnt Signaling Pathway, Planar Cell Polarity Pathway Non-canonical Wnt Signaling Pathway Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Proteasomal Protein Catabolic Process
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