SMYD1 and FAM83A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMYD1	FAM83A
Description		SET and MYND domain containing 1	family with sequence similarity 83 member A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Mitochondrion
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K4 Trimethyltransferase Activity	Protein Binding Protein Kinase Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of DNA-templated Transcription	Epidermal Growth Factor Receptor Signaling Pathway Cell Population Proliferation White Fat Cell Differentiation Positive Regulation Of Adipose Tissue Development
Pathways		Cardiogenesis	Signaling by EGFR
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)	Urinary uromodulin levels ( 24578125)
Interacting Genes		45 interacting genes: ARID5A BACH2 BHLHE40 C11orf16 CCDC33 CFAP263 CFAP68 CFTR CIMIP2A DISC1 DVL1 FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU2AF2 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44	23 interacting genes: BHLHE40 CYSRT1 DAZAP2 FOXH1 FOXI1 GCC1 GPSM1 KRT34 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MGAT5B NCK2 PLAGL2 PPP1R16B PRDM14 PSMA3 QARS1 SMYD1 TRIM23 TRIM27 UBASH3A
Entrez ID		150572	84985
HPRD ID		06025	17489
Ensembl ID		ENSG00000115593	ENSG00000147689
Uniprot IDs		E9PHG3 Q8NB12	Q86UY5
PDB IDs			4URJ
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Protein Decrotonylase Activity Histone Decrotonylase Activity Protein De-2-hydroxyisobutyrylase Activity Protein Lysine Delactylase Activity Axonemal A Tubule Inner Sheath Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Deacetylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Sperm Flagellum Cilium Movement Involved In Cell Motility Circadian Rhythm Protein Lysine Deacetylase Activity Microtubule-based Movement	Intermediate Filament Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
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