SMYD1 and H3F3C

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		SMYD1	H3F3C
Gene Name		SET and MYND domain containing 1	H3 histone, family 3C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleosome Nuclear Euchromatin
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding	Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ADSS BHLHE40 C11orf16 C11orf53 CCDC113 FAM204A H3F3C HDAC2 HDAC3 HOMEZ LENG8 MYH7B NACA OGDHL RBM4B TTC33 UTP14A WDR77 ZBTB44	12 interactors: KAT6A KDM1A KDM4B NASP PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1 WHSC1L1
Entrez ID		150572	440093
HPRD ID		06025	18443
Ensembl ID		ENSG00000115593	ENSG00000188375
Uniprot IDs		E9PHG3 Q5HYE8 Q8NB12	Q6NXT2
PDB IDs			3KV4
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Circadian Rhythm RNA Metabolic Process Rhythmic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone H4 Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Histone H3 Deacetylation Nitrogen Compound Metabolic Process Histone H3-K9 Modification Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Histone Deacetylation Regulation Of Developmental Growth Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Response To Ammonium Ion Regulation Of Striated Muscle Cell Differentiation RNA Biosynthetic Process Regulation Of Circadian Rhythm Maintenance Of Chromatin Silencing 'de Novo' AMP Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression Response To Abiotic Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development AMP Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Regulation Of Muscle Cell Differentiation Aspartate Metabolic Process Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Morphogenesis	Chromatin Modification Chromatin Organization Chromosome Organization Histone Modification Histone Methylation Protein Methylation Methylation Organelle Organization Peptidyl-amino Acid Modification Histone Lysine Methylation Peptidyl-lysine Methylation Peptidyl-lysine Modification Histone H4-R3 Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation Cellular Protein Modification Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-lysine Dimethylation Protein Metabolic Process Nucleosome Assembly Regulation Of Metabolic Process Chromatin Assembly
Tagcloud ?		adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Difference) ?		adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Intersection) ?