SYN3 and NOS1AP

Number of citations of the paper that reports this interaction (PMID 11867766)
19

Data Source:
HPRD (in vivo)

		SYN3	NOS1AP
Gene Name		synapsin III	nitric oxide synthase 1 (neuronal) adaptor protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Synaptic Vesicle Cell Junction Synaptic Vesicle Membrane	Nucleus Mitochondrion Cytosol Caveola Z Disc T-tubule Nuclear Membrane Sarcoplasmic Reticulum Membrane Sarcolemma Perinuclear Region Of Cytoplasm Inward Rectifier Potassium Channel Complex L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Catalytic Activity ATP Binding	Nitric-oxide Synthase Binding
	Biological Process	Neurotransmitter Secretion Metabolic Process Regulation Of Synaptic Transmission, GABAergic	Regulation Of Heart Rate By Chemical Signal Positive Regulation Of Gene Expression Positive Regulation Of Nitric Oxide Mediated Signal Transduction Regulation Of Apoptotic Process Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Cardiac Muscle Cell Action Potential Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Peptidyl-cysteine S-nitrosylation
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Age-related macular degeneration ( 20385819) Height ( 21998595 20881960)	Electrocardiographic traits ( 20062061 20062063) Obesity-related traits ( 23251661) QT interval ( 23166209 20031603 16648850 22726844 19305408 19305409 19587794) Word reading ( 23738518)
Protein-Protein Interactions		3 interactors: NOS1AP SYN1 SYN2	11 interactors: APP FAM133A LRP1 LRP2 LRP8 NOS1 RASD1 SYN1 SYN2 SYN3 TRAF4
Entrez ID		8224	9722
HPRD ID		04083	12023
Ensembl ID		ENSG00000185666	ENSG00000198929
Uniprot IDs		O14994 Q17R54 Q59EX7	O75052
PDB IDs		2P0A
Enriched GO Terms of Interacting Partners?		Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Positive Regulation Of Nitric Oxide Mediated Signal Transduction Neurotransmitter Transport Positive Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Heart Rate By Chemical Signal Secretion By Cell Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Synaptic Transmission Secretion Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Membrane Repolarization Positive Regulation Of Monooxygenase Activity Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Positive Regulation Of Cation Channel Activity Regulation Of Synaptic Vesicle Exocytosis Cell-cell Signaling Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Oxidoreductase Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Synaptic Vesicle Transport Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Neurotransmitter Secretion Regulation Of Heart Rate Regulation Of Oxidoreductase Activity Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Exocytosis Regulation Of Reactive Oxygen Species Metabolic Process Establishment Of Localization In Cell	Regulation Of Neurotransmitter Levels Signaling Cell Communication Phototransduction, Visible Light Retinoid Metabolic Process Regulation Of Synaptic Transmission Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Response To Light Stimulus Neurotransmitter Secretion Detection Of Light Stimulus Isoprenoid Metabolic Process Nitric Oxide Mediated Signal Transduction Response To Radiation Neurotransmitter Transport Secretion By Cell Response To Abiotic Stimulus Detection Of Abiotic Stimulus Regulation Of Signaling Secretion Endocytosis Steroid Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Alcohol Metabolic Process Receptor-mediated Endocytosis Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Ammon Gyrus Development Beta-amyloid Clearance Regulation Of Cellular Amino Acid Metabolic Process Blood Coagulation Hemostasis Forebrain Development Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Synaptic Growth At Neuromuscular Junction Regulation Of Cellular Ketone Metabolic Process Cholesterol Metabolic Process Transport Positive Regulation Of Protein Metabolic Process Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Negative Regulation Of Serotonin Uptake Sterol Metabolic Process Lipid Metabolic Process Detection Of Stimulus Regulation Of Body Fluid Levels Second-messenger-mediated Signaling
Tagcloud ?			accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn impa2 metabotropic ncam1 nd4 ndufv2 nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah
Tagcloud (Difference) ?			accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn impa2 metabotropic ncam1 nd4 ndufv2 nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah
Tagcloud (Intersection) ?