SYN3 and SYN1

Number of citations of the paper that reports this interaction (PMID 10358015)
11

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SYN3	SYN1
Gene Name		synapsin III	synapsin I
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Synaptic Vesicle Cell Junction Synaptic Vesicle Membrane	Golgi Apparatus Cytosol Synaptic Vesicle Cell Junction Dendrite
	Molecular Function	Catalytic Activity ATP Binding	Actin Binding Catalytic Activity Transporter Activity Protein Binding ATP Binding Protein Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Neurotransmitter Secretion Metabolic Process Regulation Of Synaptic Transmission, GABAergic	Synaptic Transmission Neurotransmitter Secretion Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Synaptic Vesicle Exocytosis
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses	Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Age-related macular degeneration ( 20385819) Height ( 21998595 20881960)
Protein-Protein Interactions		3 interactors: NOS1AP SYN1 SYN2	30 interactors: AMPH BIN1 BLM CAMK1 CAMK2G CDK5 CRK ERG GRB2 ITSN2 KAT5 MAPK3 NOS1 NOS1AP PAK1 PAK2 PAK3 PFN2 PIK3R1 PLCG1 PRKACA RASA1 S100A1 SH3GL2 SNCA SPTAN1 SRC SYN2 SYN3 VIM
Entrez ID		8224	6853
HPRD ID		04083	02433
Ensembl ID		ENSG00000185666	ENSG00000008056
Uniprot IDs		O14994 Q17R54 Q59EX7	P17600
PDB IDs		2P0A
Enriched GO Terms of Interacting Partners?		Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Positive Regulation Of Nitric Oxide Mediated Signal Transduction Neurotransmitter Transport Positive Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Heart Rate By Chemical Signal Secretion By Cell Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Synaptic Transmission Secretion Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Membrane Repolarization Positive Regulation Of Monooxygenase Activity Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Positive Regulation Of Cation Channel Activity Regulation Of Synaptic Vesicle Exocytosis Cell-cell Signaling Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Oxidoreductase Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Synaptic Vesicle Transport Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Neurotransmitter Secretion Regulation Of Heart Rate Regulation Of Oxidoreductase Activity Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Exocytosis Regulation Of Reactive Oxygen Species Metabolic Process Establishment Of Localization In Cell	Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Positive Regulation Of Catalytic Activity Endocytosis Positive Regulation Of Metabolic Process Regulation Of Cellular Component Organization Axon Guidance Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Metabolic Process Chemotaxis Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Axonogenesis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Transport Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Axon Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Locomotion Cell Differentiation Positive Regulation Of Cellular Metabolic Process Signaling Regulation Of Protein Phosphorylation Neuron Projection Morphogenesis Regulation Of Signaling Nervous System Development Neurotrophin TRK Receptor Signaling Pathway Cell Communication Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Neurotrophin Signaling Pathway Regulation Of Cytoskeleton Organization Regulation Of Organelle Organization T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Actin Filament-based Process Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Protein Metabolic Process
Tagcloud ?			anthropometry bf bifidobacterium bifidogenic breastfed breastfeeding carbohydrates closer colonized digestive faecal fermentable formula formulas infant inulin microbiota nct00808756 newborns oligofructose orafti prebiotic softer sterile stool stools supplemented synergy1 try
Tagcloud (Difference) ?			anthropometry bf bifidobacterium bifidogenic breastfed breastfeeding carbohydrates closer colonized digestive faecal fermentable formula formulas infant inulin microbiota nct00808756 newborns oligofructose orafti prebiotic softer sterile stool stools supplemented synergy1 try
Tagcloud (Intersection) ?