NOS1AP and RASD1

Number of citations of the paper that reports this interaction (PMID 11086993)
65

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		NOS1AP	RASD1
Gene Name		nitric oxide synthase 1 (neuronal) adaptor protein	RAS, dexamethasone-induced 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Caveola Z Disc T-tubule Nuclear Membrane Sarcoplasmic Reticulum Membrane Sarcolemma Perinuclear Region Of Cytoplasm Inward Rectifier Potassium Channel Complex L-type Voltage-gated Calcium Channel Complex	Nucleus Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Nitric-oxide Synthase Binding	GTPase Activity GTP Binding
	Biological Process	Regulation Of Heart Rate By Chemical Signal Positive Regulation Of Gene Expression Positive Regulation Of Nitric Oxide Mediated Signal Transduction Regulation Of Apoptotic Process Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Cardiac Muscle Cell Action Potential Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Peptidyl-cysteine S-nitrosylation	Signal Transduction G-protein Coupled Receptor Signaling Pathway Nitric Oxide Mediated Signal Transduction Small GTPase Mediated Signal Transduction Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Electrocardiographic traits ( 20062061 20062063) Obesity-related traits ( 23251661) QT interval ( 23166209 20031603 16648850 22726844 19305408 19305409 19587794) Word reading ( 23738518)	Coronary heart disease ( 21378990)
Protein-Protein Interactions		11 interactors: APP FAM133A LRP1 LRP2 LRP8 NOS1 RASD1 SYN1 SYN2 SYN3 TRAF4	10 interactors: GNAI1 GNAI2 GNB1 HNRNPK MATR3 NOS1 NOS1AP PLSCR1 RBMY1F TRIM37
Entrez ID		9722	51655
HPRD ID		12023	08958
Ensembl ID		ENSG00000198929	ENSG00000108551
Uniprot IDs		O75052	Q9Y272
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Neurotransmitter Levels Signaling Cell Communication Phototransduction, Visible Light Retinoid Metabolic Process Regulation Of Synaptic Transmission Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Response To Light Stimulus Neurotransmitter Secretion Detection Of Light Stimulus Isoprenoid Metabolic Process Nitric Oxide Mediated Signal Transduction Response To Radiation Neurotransmitter Transport Secretion By Cell Response To Abiotic Stimulus Detection Of Abiotic Stimulus Regulation Of Signaling Secretion Endocytosis Steroid Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Alcohol Metabolic Process Receptor-mediated Endocytosis Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Ammon Gyrus Development Beta-amyloid Clearance Regulation Of Cellular Amino Acid Metabolic Process Blood Coagulation Hemostasis Forebrain Development Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Synaptic Growth At Neuromuscular Junction Regulation Of Cellular Ketone Metabolic Process Cholesterol Metabolic Process Transport Positive Regulation Of Protein Metabolic Process Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Negative Regulation Of Serotonin Uptake Sterol Metabolic Process Lipid Metabolic Process Detection Of Stimulus Regulation Of Body Fluid Levels Second-messenger-mediated Signaling	Blood Coagulation Hemostasis Platelet Activation Regulation Of Generation Of L-type Calcium Current Regulation Of Body Fluid Levels Wound Healing Response To Wounding Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Acetylcholine Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Calcium Ion Transport Cell Activation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transport Negative Regulation Of Synaptic Transmission Regulation Of Cyclase Activity Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Nitric Oxide Mediated Signal Transduction Positive Regulation Of Protein Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Peptidyl-cysteine S-nitrosylation Negative Regulation Of Serotonin Uptake Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Histone H2A-K119 Monoubiquitination Synaptic Transmission Positive Regulation Of Cellular Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Ion Transport Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Catalytic Activity Positive Regulation Of Gene Expression Regulation Of Heart Contraction Regulation Of Signal Transduction Peptidyl-cysteine S-nitrosylation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transport Negative Regulation Of Centriole Replication Regulation Of Adrenergic Receptor Signaling Pathway Phosphatidylserine Biosynthetic Process
Tagcloud ?		accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn impa2 metabotropic ncam1 nd4 ndufv2 nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah	aci bcl behind carcinogenesis chemoprevention chemopreventive develops dysregulated dysregulation e2 ellagic eralpha examining foxo1 foxo3a insights mammary mechanistic mir mirna mirnas modulated persisted reversed reversing signature systematic tumorigenesis w
Tagcloud (Difference) ?		accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn impa2 metabotropic ncam1 nd4 ndufv2 nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah	aci bcl behind carcinogenesis chemoprevention chemopreventive develops dysregulated dysregulation e2 ellagic eralpha examining foxo1 foxo3a insights mammary mechanistic mir mirna mirnas modulated persisted reversed reversing signature systematic tumorigenesis w
Tagcloud (Intersection) ?