SYN3 and SYN2

Number of citations of the paper that reports this interaction (PMID 10358015)
11

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SYN3	SYN2
Gene Name		synapsin III	synapsin II
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Synaptic Vesicle Cell Junction Synaptic Vesicle Membrane	Cell Junction Synaptic Vesicle Membrane Synapse
	Molecular Function	Catalytic Activity ATP Binding	Catalytic Activity ATP Binding
	Biological Process	Neurotransmitter Secretion Metabolic Process Regulation Of Synaptic Transmission, GABAergic	Synaptic Transmission Neurotransmitter Secretion Metabolic Process
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Age-related macular degeneration ( 20385819) Height ( 21998595 20881960)	Fasting insulin-related traits (interaction with BMI) ( 22581228) Platelet counts ( 22139419) Type 2 diabetes ( 18372903)
Protein-Protein Interactions		3 interactors: NOS1AP SYN1 SYN2	6 interactors: NOS1AP PRKACA SYN1 SYN3 YWHAE YWHAZ
Entrez ID		8224	6854
HPRD ID		04083	02857
Ensembl ID		ENSG00000185666
Uniprot IDs		O14994 Q17R54 Q59EX7	Q86VA8
PDB IDs		2P0A
Enriched GO Terms of Interacting Partners?		Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Positive Regulation Of Nitric Oxide Mediated Signal Transduction Neurotransmitter Transport Positive Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Heart Rate By Chemical Signal Secretion By Cell Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Synaptic Transmission Secretion Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Membrane Repolarization Positive Regulation Of Monooxygenase Activity Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Positive Regulation Of Cation Channel Activity Regulation Of Synaptic Vesicle Exocytosis Cell-cell Signaling Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Oxidoreductase Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Synaptic Vesicle Transport Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Neurotransmitter Secretion Regulation Of Heart Rate Regulation Of Oxidoreductase Activity Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Exocytosis Regulation Of Reactive Oxygen Species Metabolic Process Establishment Of Localization In Cell	Regulation Of Heart Rate Regulation Of Heart Rate By Chemical Signal Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Signaling Regulation Of Heart Contraction Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Membrane Repolarization Positive Regulation Of Transport Positive Regulation Of Intracellular Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell-cell Signaling Regulation Of Potassium Ion Transmembrane Transport Regulation Of Synaptic Transmission Regulation Of Cellular Localization Cardiac Conduction Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transport Regulation Of Ion Transmembrane Transport Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Regulation Of Cation Channel Activity Secretion By Cell Regulation Of Apoptotic Process Regulation Of Mitochondrion Organization Regulation Of Cell Death Positive Regulation Of Nitric Oxide Mediated Signal Transduction Positive Regulation Of Dense Core Granule Biogenesis Neurotransmitter Secretion Regulation Of Ion Transport Secretion G2/M Transition Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Positive Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Heart Rate By Hormone Histone H3-T6 Phosphorylation Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Neurotransmitter Levels Establishment Of Localization In Cell Regulation Of Protein Localization Neurotransmitter Transport Membrane Organization Regulation Of Generation Of L-type Calcium Current Golgi Reassembly
Tagcloud ?			agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?			agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?