NOS1AP

Name	nitric oxide synthase 1 adaptor protein
Structure	No pdb structure
Interactors	18 interactors: AKNAD1 APP CKM FYN HSPD1 LRP1 LRP2 LRP8 NHP2 NOS1 PLAGL2 PNP RASD1 RYBP SYN1 SYN2 SYN3 TRAF4
GO Annotations	Cellular Component	Podosome Nucleus Mitochondrion Cytosol Caveola Z Disc Filopodium T-tubule Nuclear Membrane Sarcoplasmic Reticulum Membrane Sarcolemma Cell Projection Perinuclear Region Of Cytoplasm Anchoring Junction Glutamatergic Synapse
	Molecular Function	Protein Binding Nitric-oxide Synthase Regulator Activity Signaling Adaptor Activity Nitric-oxide Synthase Binding
	Biological Process	Regulation Of Heart Rate By Chemical Signal Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Cardiac Muscle Cell Action Potential Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Positive Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential
GWAS	Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600 ) Body mass index (change over time) ( 25133637 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Electrocardiographic traits ( 20062061 20062063 25055868 ) Electrocardiographic traits (multivariate) ( 32602732 ) Granulocyte percentage of myeloid white cells ( 27863252 ) Heel bone mineral density ( 30598549 ) Iris color (L* coordinate) ( 30895295 ) Lateral ventricle temporal horn volume ( 31530798 ) Long QT syndrome ( 32429735 ) Mean platelet volume ( 32888494 ) Mean reticulocyte volume ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Monocyte count ( 32888494 ) Monocyte percentage of white cells ( 32888494 27863252 ) Mosquito bite size ( 28199695 ) Obesity-related traits ( 23251661 ) QT interval ( 19305408 19305409 19587794 30679814 16648850 29874175 29213071 20031603 22726844 23166209 24952745 ) Sum of carotid plaque area ( 32469969 ) Sum of stenosis ( 32469969 ) T wave morphology restitution during exercise ( 31607149 ) T wave morphology restitution during exercise (MTAG) ( 31607149 ) T wave morphology restitution during recovery from exercise ( 31607149 ) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149 ) Word reading ( 23738518 )
Entrez ID	9722
HPRD ID	12023
Ensembl ID	ENSG00000198929
Uniprot IDs	O75052
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Apolipoprotein Binding Synaptic Vesicle Cycle Synaptic Vesicle Clustering Low-density Lipoprotein Particle Receptor Activity Clathrin-coated Pit Synaptic Signaling Cargo Receptor Activity Schaffer Collateral - CA1 Synapse Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Astrocyte Activation Involved In Immune Response Postsynaptic Density Cellular Response To Growth Factor Stimulus Growth Factor Receptor Binding Positive Regulation Of Lysosomal Protein Catabolic Process Neurotransmitter Secretion Chemical Synaptic Transmission Response To Growth Factor Trans-synaptic Signaling Cellular Response To Amyloid-beta Positive Regulation Of Protein Catabolic Process In The Vacuole Cell-cell Signaling Regulation Of Protein Catabolic Process Signaling Response To Amyloid-beta Cell Communication Receptor Complex High-density Lipoprotein Particle Binding Regulation Of Lysosomal Protein Catabolic Process Retinoid Metabolic Process Reelin-mediated Signaling Pathway Diterpenoid Metabolic Process Cell Body Regulation Of Dendritic Spine Maintenance Calcium-dependent Protein Binding Dendrite Extrinsic Component Of Synaptic Vesicle Membrane Vesicle-mediated Transport Modulation Of Chemical Synaptic Transmission Synapse Organization Terpenoid Metabolic Process Vesicle-mediated Transport In Synapse Protein-folding Chaperone Binding Heparan Sulfate Proteoglycan Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Neuron Projection Morphogenesis Astrocyte Activation Layer Formation In Cerebral Cortex Isoprenoid Metabolic Process Neurotransmitter Transport