USP5 and DAZAP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		USP5	DAZAP2
Gene Name		ubiquitin specific peptidase 5 (isopeptidase T)	DAZ associated protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome	Nucleus Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Omega Peptidase Activity Zinc Ion Binding	Protein Binding WW Domain Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: APP DAZAP2 DVL2 PJA1 PLA2G2A RFFL RNF11 STK33 TADA3 TMEM239 TRAF6 TRIM26 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIML1 UBC UBE2S UBTD2 USP28	86 interactors: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FAM46B FAM46C FBN3 GPSM1 HGS HIP1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MED31 NDUFA5 NEDD4 NEDD4L NOC4L OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPT2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		8078	9802
HPRD ID		03265	08463
Ensembl ID		ENSG00000111667	ENSG00000183283
Uniprot IDs		P45974	E9PB45 Q15038
PDB IDs		2DAG 2DAK 2G43 2G45 3IHP
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Catabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K63-linked Ubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Ubiquitination Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Viral Release From Host Cell Apoptotic Process Negative Regulation Of Viral Entry Into Host Cell Programmed Cell Death Proteolysis Cell Death Regulation Of Lipopolysaccharide-mediated Signaling Pathway Death Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteolysis Regulation Of Viral Release From Host Cell Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Response To Cytokine Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Activation Of Innate Immune Response Cellular Metabolic Process Innate Immune Response Positive Regulation Of MAPK Cascade Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Phosphorylation Cytokine-mediated Signaling Pathway Positive Regulation Of Innate Immune Response Defense Response Protein Autoubiquitination	Negative Regulation Of Signal Transduction Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Protein Processing Regulation Of ERBB Signaling Pathway Protein Ubiquitination Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Polyubiquitination Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Virion Assembly Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Signaling Intracellular Transport Of Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Protein Metabolic Process RNA Biosynthetic Process Endosomal Transport Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type I Interferon Production Transforming Growth Factor Beta Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Tagcloud ?		acquired add already alternate alters braf checkpoint damaging deubiquitinase dub eoai3402143 fas intrinsically knockdown mek melanoma modulating nras overcame p73 phenocopied restored sensitization sensitized strand suppress ub unanchored vemurafenib
Tagcloud (Difference) ?		acquired add already alternate alters braf checkpoint damaging deubiquitinase dub eoai3402143 fas intrinsically knockdown mek melanoma modulating nras overcame p73 phenocopied restored sensitization sensitized strand suppress ub unanchored vemurafenib
Tagcloud (Intersection) ?