USP5 and STK33

Number of citations of the paper that reports this interaction (PMID 22451720)
3

Data Source:
BioGRID (pull down)

		USP5	STK33
Gene Name		ubiquitin specific peptidase 5 (isopeptidase T)	serine/threonine kinase 33
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome	Perinuclear Region Of Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Omega Peptidase Activity Zinc Ion Binding	Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Deubiquitination	Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS			Body mass index ( 19079261)
Protein-Protein Interactions		22 interactors: APP DAZAP2 DVL2 PJA1 PLA2G2A RFFL RNF11 STK33 TADA3 TMEM239 TRAF6 TRIM26 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIML1 UBC UBE2S UBTD2 USP28	4 interactors: APP GLYCTK USP15 USP5
Entrez ID		8078	65975
HPRD ID		03265	09642
Ensembl ID		ENSG00000111667	ENSG00000130413
Uniprot IDs		P45974	Q9BYT3
PDB IDs		2DAG 2DAK 2G43 2G45 3IHP
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Catabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K63-linked Ubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Ubiquitination Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Viral Release From Host Cell Apoptotic Process Negative Regulation Of Viral Entry Into Host Cell Programmed Cell Death Proteolysis Cell Death Regulation Of Lipopolysaccharide-mediated Signaling Pathway Death Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteolysis Regulation Of Viral Release From Host Cell Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Response To Cytokine Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Activation Of Innate Immune Response Cellular Metabolic Process Innate Immune Response Positive Regulation Of MAPK Cascade Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Phosphorylation Cytokine-mediated Signaling Pathway Positive Regulation Of Innate Immune Response Defense Response Protein Autoubiquitination	Regulation Of Proteolysis Protein Deubiquitination Protein Modification By Small Protein Removal Synaptic Growth At Neuromuscular Junction Histone H2B Conserved C-terminal Lysine Deubiquitination Cellular Protein Modification Process Regulation Of Proteasomal Protein Catabolic Process Collateral Sprouting In Absence Of Injury Protein Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cellular Protein Metabolic Process Neuron Remodeling Monoubiquitinated Protein Deubiquitination Regulation Of Protein Catabolic Process Phosphorylation Regulation Of Cellular Protein Metabolic Process Pathway-restricted SMAD Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Deubiquitination Regulation Of Protein Metabolic Process Protein Metabolic Process Cellular Copper Ion Homeostasis Proteolysis Involved In Cellular Protein Catabolic Process Histone Deubiquitination Cellular Protein Catabolic Process Copper Ion Homeostasis Suckling Behavior Protein Catabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Phosphate-containing Compound Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Macromolecule Catabolic Process Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development
Tagcloud ?		acquired add already alternate alters braf checkpoint damaging deubiquitinase dub eoai3402143 fas intrinsically knockdown mek melanoma modulating nras overcame p73 phenocopied restored sensitization sensitized strand suppress ub unanchored vemurafenib
Tagcloud (Difference) ?		acquired add already alternate alters braf checkpoint damaging deubiquitinase dub eoai3402143 fas intrinsically knockdown mek melanoma modulating nras overcame p73 phenocopied restored sensitization sensitized strand suppress ub unanchored vemurafenib
Tagcloud (Intersection) ?