TSGA10 and CBX8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TSGA10	CBX8
Gene Name		testis specific, 10	chromobox homolog 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Motile Cilium Nuclear Membrane Neuron Projection	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Molecular_function	Single-stranded RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Methylated Histone Binding
	Biological Process	Spermatogenesis Cell Projection Assembly	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Ubiquitination
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		38 interactors: AES BCL6B BIRC2 CBX8 CCDC33 CCHCR1 CDC73 CDK18 CEP44 CEP57L1 CREB5 FAM161A FBF1 FLJ38668 HIF1A MID2 PPHLN1 PPP1R18 PRPF31 RCOR3 RTP5 SCEL SPERT SYT6 TCEA2 TRIM29 ZBTB24 ZBTB38 ZNF124 ZNF2 ZNF410 ZNF417 ZNF426 ZNF490 ZNF544 ZNF587 ZNF599 ZNF670	42 interactors: BMI1 CALCOCO2 CCDC136 CCDC57 EEF1G FSD2 GOLGA2 GPRASP2 HAP1 HIST3H3 HMBOX1 IKZF1 KAT5 KAT7 KCTD9 KIFC3 KRT40 LZTS2 MID2 MLLT1 MLLT3 MTUS2 PAXIP1 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC2 PNMA2 RING1 RNF2 RPGRIP1 SETDB1 SOX5 TFCP2 TRAF2 TSGA10 UNC119 USP11 USP7 ZBTB14
Entrez ID		80705	57332
HPRD ID		06202	13006
Ensembl ID		ENSG00000135951
Uniprot IDs		Q9BZW7	Q9HC52
PDB IDs			3I91
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Cellular Process Histone Ubiquitination Negative Regulation Of Gene Expression Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination Neural Fold Elevation Formation Negative Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription, DNA-templated Elastin Metabolic Process Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Chemokine-mediated Signaling Pathway Acrosomal Vesicle Exocytosis Vascular Endothelial Growth Factor Production Negative Regulation Of Cellular Metabolic Process Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Positive Regulation Of Anoikis Intestinal Epithelial Cell Maturation Regulation Of Protein Monoubiquitination Response To Interleukin-1 Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Ubiquitination	Transcription, DNA-templated RNA Biosynthetic Process Histone Modification Chromatin Modification Chromosome Organization Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Ubiquitination Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Histone H2A Monoubiquitination Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Histone H2A Ubiquitination Peptidyl-lysine Modification Regulation Of Metabolic Process Histone Monoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Organelle Organization Histone Acetylation Protein Modification By Small Protein Conjugation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Monoubiquitination Anterior/posterior Pattern Specification Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Segment Specification Cellular Protein Modification Process Cellular Response To Reactive Oxygen Species
Tagcloud ?		always applicable axis cytometry dimension discovered escc esccs esophageal inactivation influenced interactive latter malignancy manipulation microrna mir negatively nude obligatory originally promoted rb regulating restricted testis turn uniformly utr	aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Difference) ?		always applicable axis cytometry dimension discovered escc esccs esophageal inactivation influenced interactive latter malignancy manipulation microrna mir negatively nude obligatory originally promoted rb regulating restricted testis turn uniformly utr	aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Intersection) ?