TSGA10 and ZNF205

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSGA10	ZNF205
Description		testis specific 10	zinc finger protein 205
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton Motile Cilium Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece	Nucleus Mitochondrion
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Spermatogenesis Cell Projection Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		81 interacting genes: AARD AXIN1 AXIN2 BCL6B BIRC2 CBX8 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC73 CDK18 CDSN CEP44 CEP57 CEP57L1 COG6 CREB5 DISC1 FAM161A FAM161B FBF1 GCC2-AS1 GOLGA2 HDAC4 HDX HIF1A HNRNPM HOOK2 JRK KANK2 KIAA1328 KRT6A KRT76 LMNA LZTS1 MAD1L1 MATR3 MBD3L1 MID2 NAB2 PAK5 PIBF1 PKN1 PLEKHA7 PPHLN1 PPP1R13B PPP1R18 PRDM14 PRDM6 PRPF31 RBAK RCOR3 RNF6 RTP5 SCEL SORBS3 SYT6 TCEA2 TLE5 TP53BP2 TRIM14 TRIM29 ZBTB24 ZBTB26 ZBTB38 ZBTB39 ZNF124 ZNF2 ZNF205 ZNF23 ZNF410 ZNF417 ZNF426 ZNF438 ZNF490 ZNF544 ZNF587 ZNF599 ZNF670	17 interacting genes: C8orf33 CALCOCO2 CCDC85B CDC37 GOLGA6L9 HDAC6 ILK MAPK6 MDFI MEST PICK1 TNS2 TRAF2 TSGA10 UBQLN2 UBQLN4 WT1
Entrez ID		80705	7755
HPRD ID		06202	04580
Ensembl ID		ENSG00000135951	ENSG00000122386
Uniprot IDs		A0A218MIY9 Q9BZW7	O95201
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Primary Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Identical Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process DNA Binding Negative Regulation Of Biosynthetic Process Centrosome Negative Regulation Of Metabolic Process P53 Binding Negative Regulation Of Macromolecule Metabolic Process Microtubule Binding Metal Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Wnt Signaling Pathway	Regulation Of Macroautophagy Polyubiquitin Modification-dependent Protein Binding Regulation Of Autophagy Positive Regulation Of Type 2 Mitophagy Autophagosome Regulation Of Autophagosome Maturation Positive Regulation Of Macroautophagy Autophagy Positive Regulation Of Mitophagy Regulation Of Protein-containing Complex Disassembly Positive Regulation Of Autophagy Of Mitochondrion Dendritic Spine Organization Branching Involved In Ureteric Bud Morphogenesis Protein Kinase Binding Cytoplasm TORC2 Complex Disassembly Negative Regulation Of Cell Growth Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Neuron Projection Organization Postsynapse Organization Regulation Of Mitophagy Positive Regulation Of Autophagy Negative Regulation Of Macroautophagy Polyubiquitinated Misfolded Protein Transport Hsp90 Protein Binding Positive Regulation Of Cholangiocyte Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Glial Cell Development Septin Cytoskeleton Regulation Of Cellular Component Organization TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Negative Regulation Of Growth Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Positive Regulation Of Cellular Response To Oxidative Stress Acetylspermidine Deacetylase Activity Polyamine Deacetylation Positive Regulation Of Catabolic Process Spermidine Deacetylation Peroxidase Inhibitor Activity Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Aggrephagy Tubulin Deacetylase Activity HSP90-CDC37 Chaperone Complex Negative Regulation Of G Protein-coupled Receptor Internalization Nuclear Proteasome Complex
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