TSGA10 and ZBTB39

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSGA10	ZBTB39
Description		testis specific 10	zinc finger and BTB domain containing 39
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton Motile Cilium Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece	Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Spermatogenesis Cell Projection Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 27611488 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		81 interacting genes: AARD AXIN1 AXIN2 BCL6B BIRC2 CBX8 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC73 CDK18 CDSN CEP44 CEP57 CEP57L1 COG6 CREB5 DISC1 FAM161A FAM161B FBF1 GCC2-AS1 GOLGA2 HDAC4 HDX HIF1A HNRNPM HOOK2 JRK KANK2 KIAA1328 KRT6A KRT76 LMNA LZTS1 MAD1L1 MATR3 MBD3L1 MID2 NAB2 PAK5 PIBF1 PKN1 PLEKHA7 PPHLN1 PPP1R13B PPP1R18 PRDM14 PRDM6 PRPF31 RBAK RCOR3 RNF6 RTP5 SCEL SORBS3 SYT6 TCEA2 TLE5 TP53BP2 TRIM14 TRIM29 ZBTB24 ZBTB26 ZBTB38 ZBTB39 ZNF124 ZNF2 ZNF205 ZNF23 ZNF410 ZNF417 ZNF426 ZNF438 ZNF490 ZNF544 ZNF587 ZNF599 ZNF670	11 interacting genes: AQP1 DRC4 IL16 KDM1A PLK4 PSMD2 SUMO2 SUMO3 TCEANC TRIM41 TSGA10
Entrez ID		80705	9880
HPRD ID		06202	13796
Ensembl ID		ENSG00000135951	ENSG00000166860
Uniprot IDs		A0A218MIY9 Q9BZW7	O15060
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Primary Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Identical Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process DNA Binding Negative Regulation Of Biosynthetic Process Centrosome Negative Regulation Of Metabolic Process P53 Binding Negative Regulation Of Macromolecule Metabolic Process Microtubule Binding Metal Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Wnt Signaling Pathway	Protein Tag Activity Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Cellular Response To CAMP Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Ubiquitin-like Protein Ligase Binding Protein Sumoylation Nitric Oxide Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cellular Response To UV Metanephric Glomerulus Vasculature Development Cerebrospinal Fluid Secretion Renal Water Absorption Carbon Dioxide Transmembrane Transporter Activity Positive Regulation Of Saliva Secretion Response To Purine-containing Compound Glomerulus Vasculature Development Water Transmembrane Transporter Activity Regulation Of Cell Size Cellular Response To Light Stimulus Nucleus Cellular Response To Mercury Ion Transepithelial Water Transport Hydrogen Peroxide Transmembrane Transport Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Intracellularly CGMP-activated Cation Channel Activity Response To CAMP Carbon Dioxide Transmembrane Transport Lipid Digestion Glycerol Transmembrane Transporter Activity Corticotropin Secretion Pancreatic Juice Secretion Positive Regulation Of Protein Localization To Cilium Positive Regulation Of Neutrophil Activation Proteasome Storage Granule Protein Modification Process PML Body De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Procentriole Replication Complex Procentriole Deuterosome Response To Fungicide MRF Binding Guanine Metabolic Process Protein Demethylase Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity
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