TSGA10 and RNF6

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		TSGA10	RNF6
Description		testis specific 10	ring finger protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton Motile Cilium Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece	Nucleus Cytoplasm PML Body Axon Nuclear Membrane Cell Projection
	Molecular Function	Protein Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Nuclear Androgen Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Spermatogenesis Cell Projection Assembly	Regulation Of DNA-templated Transcription Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Axon Extension Protein K27-linked Ubiquitination Positive Regulation Of DNA-templated Transcription Axon Extension Regulation Of Androgen Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Sporadic pituitary adenoma ( 26029870) Type 2 diabetes ( 24509480 28869590 30297969 30718926 32499647) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		81 interacting genes: AARD AXIN1 AXIN2 BCL6B BIRC2 CBX8 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC73 CDK18 CDSN CEP44 CEP57 CEP57L1 COG6 CREB5 DISC1 FAM161A FAM161B FBF1 GCC2-AS1 GOLGA2 HDAC4 HDX HIF1A HNRNPM HOOK2 JRK KANK2 KIAA1328 KRT6A KRT76 LMNA LZTS1 MAD1L1 MATR3 MBD3L1 MID2 NAB2 PAK5 PIBF1 PKN1 PLEKHA7 PPHLN1 PPP1R13B PPP1R18 PRDM14 PRDM6 PRPF31 RBAK RCOR3 RNF6 RTP5 SCEL SORBS3 SYT6 TCEA2 TLE5 TP53BP2 TRIM14 TRIM29 ZBTB24 ZBTB26 ZBTB38 ZBTB39 ZNF124 ZNF2 ZNF205 ZNF23 ZNF410 ZNF417 ZNF426 ZNF438 ZNF490 ZNF544 ZNF587 ZNF599 ZNF670	39 interacting genes: AHCYL1 AR CBY2 CCDC33 CCDC57 CDKN1B CEP70 GOLGA2 HOOK2 IKZF1 IKZF3 KIAA0753 KRT15 KRT40 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MTUS2 PNMA2 REL RINT1 RPGRIP1 SSX2IP STK4 STX11 TADA2A TFIP11 TNS2 TP53 TRIM23 TRIM27 TRIM37 TSGA10 UBE2C UBE2D1 UBE2H
Entrez ID		80705	6049
HPRD ID		06202	05027
Ensembl ID		ENSG00000135951	ENSG00000127870
Uniprot IDs		A0A218MIY9 Q9BZW7	A0A024RDP2 A0A0S2Z4G9 Q9Y252
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Primary Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Identical Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process DNA Binding Negative Regulation Of Biosynthetic Process Centrosome Negative Regulation Of Metabolic Process P53 Binding Negative Regulation Of Macromolecule Metabolic Process Microtubule Binding Metal Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Wnt Signaling Pathway	Identical Protein Binding Intracellular Transport Cytoskeleton Ubiquitin-protein Transferase Activity Microtubule Organizing Center Organization Cytoplasm Protein Binding Cellular Localization Establishment Of Localization In Cell Centrosome Ubiquitin Conjugating Enzyme Activity Ubiquitin Protein Ligase Activity Cell Projection Assembly Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Cellular Response To Antibiotic Cilium Assembly Negative Regulation Of Epithelial Cell Proliferation Intracellular Protein Localization Protein Ubiquitination Transcription Coactivator Activity Cilium Organization Protein Transport Negative Regulation Of Viral Transcription Regulation Of Exit From Mitosis Suppression Of Viral Release By Host Protein Modification By Small Protein Conjugation Organelle Organization Regulation Of Viral Transcription Organelle Assembly Negative Regulation Of Cell Population Proliferation Intracellular Protein Transport Protein Tetramerization Cell Differentiation Involved In Embryonic Placenta Development Plasma Membrane Bounded Cell Projection Assembly
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