DNAJC5 and VAMP1

Number of citations of the paper that reports this interaction (PubMedID 29997244)
64

Data Source:
BioGRID (fluorescent resonance energy transfer)

		DNAJC5	VAMP1
Description		DnaJ heat shock protein family (Hsp40) member C5	vesicle associated membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Lysosomal Membrane Cytosol Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Presynapse	Mitochondrion Mitochondrial Outer Membrane Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Synapse Tertiary Granule Membrane
	Molecular Function	Protein Binding ATP-dependent Protein Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Folding Exocytosis Synaptic Vesicle Exocytosis Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Neuron Apoptotic Process Regulation Of Synaptic Vesicle Cycle	Vesicle Fusion Vesicle-mediated Transport SNARE Complex Assembly
Pathways		Neutrophil degranulation GABA synthesis, release, reuptake and degradation Sensory processing of sound by inner hair cells of the cochlea	Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type G (botG)
Drugs			Botulinum toxin type B
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)	Hip geometry ( 17903296)
Interacting Genes		49 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CD2 CFTR CGB5 CLCN3 ERC1 FAS FCHO1 GRM8 HBA2 KHDC4 LIN7A LIN7C NECAP1 NRXN3 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7	37 interacting genes: AQP6 ARL13B BCAP31 CDKN2A CRB3 CREB3L1 CYB5R3 DNAJC5 EBP ELOVL4 ELOVL7 ERGIC3 FAM210B FCER1G GPR152 KASH5 LAPTM5 LMNA REEP4 RETREG3 RNF24 SCN3B SEC11C SGMS2 SLC10A6 SLC30A8 SNAP23 SNAP29 STX1A STX1B STX4 TMEM101 TMEM14B TMEM35A TMX2 VAPA VAPB
Entrez ID		80331	6843
HPRD ID		08539	01716
Ensembl ID		ENSG00000101152	ENSG00000139190
Uniprot IDs		Q9H3Z4	F5GZV7 P23763
PDB IDs		2N04 2N05
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Membrane Vesicle-mediated Transport Synapse SNARE Binding Neurotransmitter Transport SNARE Complex Secretion By Cell Exocytosis Cytoplasmic Vesicle Establishment Of Localization In Cell SNAP Receptor Activity Synaptic Vesicle Secretion Regulation Of Vesicle-mediated Transport Presynapse Protein Transport Regulation Of Exocytosis Plasma Membrane Membrane Establishment Of Protein Localization Organelle Fusion SNARE Complex Assembly Neuron Projection Vesicle Fusion Organelle Membrane Fusion Clathrin-coated Endocytic Vesicle Membrane Vesicle Organization Neurotransmitter Secretion Organelle Localization By Membrane Tethering Regulation Of Regulated Secretory Pathway Phagocytic Vesicle Glutamatergic Synapse Regulation Of Secretion By Cell Organelle Localization Membrane Docking Vesicle-mediated Transport In Synapse Membrane Fusion Regulation Of Secretion Recycling Endosome Membrane Endosome Signal Release Vesicle Docking Intracellular Protein Localization Regulation Of Transport Positive Regulation Of Exocytosis Membrane Organization Regulation Of Endocytosis Chemical Synaptic Transmission Trans-synaptic Signaling Long-term Synaptic Potentiation	Membrane Endoplasmic Reticulum Membrane SNAP Receptor Activity Organelle Localization By Membrane Tethering Membrane Docking SNARE Complex Membrane Organization Secretion By Cell Exocytosis Organelle Localization Membrane Fusion Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Signal Release Intracellular Protein Localization Endoplasmic Reticulum Vesicle Fusion To Plasma Membrane Vesicle Fusion Organelle Membrane Fusion Vesicle-mediated Transport Vesicle Organization Synaptic Vesicle Membrane Organization Positive Regulation Of Protein Localization To Cell Surface Organelle Fusion Endoplasmic Reticulum Organization Cellular Localization Establishment Of Localization In Cell FFAT Motif Binding Golgi Vesicle Transport Positive Regulation Of Protein Localization COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Synaptic Vesicle Exocytosis Sphingolipid Biosynthetic Process Cytoplasmic Vesicle Regulated Exocytosis Regulation Of Protein Localization To Cell Surface Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid ATP-dependent Protein Binding Endoplasmic Reticulum Localization Regulation Of Protein Localization Fatty Acid Elongation, Saturated Fatty Acid Protein Binding Presynapse Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of Regulated Secretory Pathway Azurophil Granule Membrane Host-mediated Activation Of Viral Genome Replication
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?