VAMP1 and SNAP23

Number of citations of the paper that reports this interaction (PMID 8663154)
53

Data Source:
HPRD (in vitro, two hybrid)

		VAMP1	SNAP23
Gene Name		vesicle-associated membrane protein 1 (synaptobrevin 1)	synaptosomal-associated protein, 23kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Integral Component Of Plasma Membrane Synaptic Vesicle Cell Surface Cell Junction Synaptic Vesicle Membrane SNARE Complex Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Tertiary Granule Membrane	Nucleoplasm Cytoplasm Plasma Membrane Focal Adhesion SNARE Complex Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Synapse Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Exocytosis Vesicle Fusion Pathogenesis SNARE Complex Assembly	Histamine Secretion By Mast Cell Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Organization Membrane Fusion
Pathways		Toxicity of botulinum toxin type G (BoNT/G) Uptake and actions of bacterial toxins Toxicity of botulinum toxin type D (BoNT/D) Toxicity of botulinum toxin type F (BoNT/F) Neurotoxicity of clostridium toxins	Translocation of GLUT4 to the plasma membrane trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Hip geometry ( 17903296)
Protein-Protein Interactions		9 interactors: BCAP31 CCDC155 SNAP23 SNAP29 STX1A STX1B STX4 VAPA VAPB	34 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP5 VAMP7 VAMP8 WASH2P
Entrez ID		6843	8773
HPRD ID		01716	03962
Ensembl ID		ENSG00000139190	ENSG00000092531
Uniprot IDs		P23763	A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Membrane Fusion Vesicle Fusion Synaptic Vesicle Exocytosis Organelle Fusion Neurotransmitter Secretion Synaptic Vesicle Transport Establishment Of Localization In Cell Establishment Of Organelle Localization Regulation Of Neurotransmitter Levels Cellular Localization Vesicle-mediated Transport Neurotransmitter Transport Organelle Localization Membrane Organization Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Transport Exocytosis Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Release From Host Cell Intracellular Transport Secretion By Cell Protein Localization Organelle Organization Synaptic Transmission Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Secretion Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Positive Regulation Of Viral Release From Host Cell Protein Transport Vesicle Docking Establishment Of Protein Localization Membrane Docking Synaptic Vesicle Priming ER To Golgi Vesicle-mediated Transport Positive Regulation Of Synaptic Transmission Cell-cell Signaling Positive Regulation Of Neurotransmitter Secretion Regulation Of Exocytosis Transport Positive Regulation Of Viral Genome Replication COPII-coated Vesicle Budding Regulation Of Viral Release From Host Cell Cellular Protein Localization Interaction With Symbiont Regulation Of Synaptic Vesicle Exocytosis	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Vesicle-mediated Transport Establishment Of Localization In Cell Exocytosis Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Transport Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Docking Secretion Protein Localization Neurotransmitter Secretion Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Synaptic Vesicle Transport Golgi Vesicle Transport Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization SNARE Complex Assembly Regulation Of Exocytosis Establishment Of Organelle Localization Organelle Organization Regulation Of Cellular Localization Cell-cell Signaling Organelle Localization Synaptic Transmission Regulation Of Secretion Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Priming Positive Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Transport Neutrophil Degranulation Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Synaptic Transmission
Tagcloud ?		adipocytes biol cellubrevin conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone localizes martin permeabilized postendocytic slot snares streptolysin tails tellam thio triphosphate vamp2	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Difference) ?		adipocytes biol conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone localizes martin permeabilized postendocytic slot streptolysin tails tellam thio triphosphate vamp2	apical brevin brevins clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Intersection) ?		cellubrevin snares