VAMP1 and BCAP31

Number of citations of the paper that reports this interaction (PMID 9396746)
35

Data Source:
HPRD (in vivo)

		VAMP1	BCAP31
Gene Name		vesicle-associated membrane protein 1 (synaptobrevin 1)	B-cell receptor-associated protein 31
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Integral Component Of Plasma Membrane Synaptic Vesicle Cell Surface Cell Junction Synaptic Vesicle Membrane SNARE Complex Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Tertiary Granule Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Particle Cytosol Integral Component Of Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Protein Binding Protein Complex Binding MHC Class I Protein Binding
	Biological Process	Exocytosis Vesicle Fusion Pathogenesis SNARE Complex Assembly	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Cytosolic Calcium Ion Concentration Spermatogenesis Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Toxicity of botulinum toxin type G (BoNT/G) Uptake and actions of bacterial toxins Toxicity of botulinum toxin type D (BoNT/D) Toxicity of botulinum toxin type F (BoNT/F) Neurotoxicity of clostridium toxins	Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase Class I MHC mediated antigen processing & presentation Antigen Presentation: Folding, assembly and peptide loading of class I MHC Adaptive Immune System
Drugs
Diseases
GWAS		Hip geometry ( 17903296)
Protein-Protein Interactions		9 interactors: BCAP31 CCDC155 SNAP23 SNAP29 STX1A STX1B STX4 VAPA VAPB	25 interactors: ACTG1 APP BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 LMAN1 MSN MYH10 PLP2 SERPINF2 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		6843	10134
HPRD ID		01716	02319
Ensembl ID		ENSG00000139190	ENSG00000185825
Uniprot IDs		P23763	P51572
PDB IDs			4JZL 4JZP
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Membrane Fusion Vesicle Fusion Synaptic Vesicle Exocytosis Organelle Fusion Neurotransmitter Secretion Synaptic Vesicle Transport Establishment Of Localization In Cell Establishment Of Organelle Localization Regulation Of Neurotransmitter Levels Cellular Localization Vesicle-mediated Transport Neurotransmitter Transport Organelle Localization Membrane Organization Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Transport Exocytosis Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Release From Host Cell Intracellular Transport Secretion By Cell Protein Localization Organelle Organization Synaptic Transmission Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Secretion Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Positive Regulation Of Viral Release From Host Cell Protein Transport Vesicle Docking Establishment Of Protein Localization Membrane Docking Synaptic Vesicle Priming ER To Golgi Vesicle-mediated Transport Positive Regulation Of Synaptic Transmission Cell-cell Signaling Positive Regulation Of Neurotransmitter Secretion Regulation Of Exocytosis Transport Positive Regulation Of Viral Genome Replication COPII-coated Vesicle Budding Regulation Of Viral Release From Host Cell Cellular Protein Localization Interaction With Symbiont Regulation Of Synaptic Vesicle Exocytosis	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Establishment Of Localization In Cell Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrion Organization Vesicle-mediated Transport Membrane Organization Cellular Localization Apoptotic Process Response To Wounding Neuron Apoptotic Process Immune System Process Programmed Cell Death Positive Regulation Of Peptidase Activity Positive Regulation Of Mitochondrion Organization Cell Death Death Neuron Death Secretion By Cell Apoptotic Mitochondrial Changes Exocytosis Apoptotic Signaling Pathway Organelle Fusion Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Transport Positive Regulation Of Cell Death Regulation Of Endopeptidase Activity Secretion Immune Response Positive Regulation Of Organelle Organization Regulation Of Peptidase Activity Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Membrane Fusion Intracellular Transport Regulation Of Protein Localization Positive Regulation Of Endopeptidase Activity
Tagcloud ?		adipocytes biol cellubrevin conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone localizes martin permeabilized postendocytic slot snares streptolysin tails tellam thio triphosphate vamp2	24h 48h anova aureus caprine cd2bp2 challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary
Tagcloud (Difference) ?		adipocytes biol cellubrevin conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone localizes martin permeabilized postendocytic slot snares streptolysin tails tellam thio triphosphate vamp2	24h 48h anova aureus caprine cd2bp2 challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary
Tagcloud (Intersection) ?