VAMP1 and TMEM35A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VAMP1	TMEM35A
Description		vesicle associated membrane protein 1	transmembrane protein 35A
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Synapse Tertiary Granule Membrane	Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding Acetylcholine Receptor Regulator Activity
	Biological Process	Vesicle Fusion Vesicle-mediated Transport SNARE Complex Assembly	Chaperone-mediated Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways		Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type G (botG)
Drugs		Botulinum toxin type B
Diseases
GWAS		Hip geometry ( 17903296)
Interacting Genes		37 interacting genes: AQP6 ARL13B BCAP31 CDKN2A CRB3 CREB3L1 CYB5R3 DNAJC5 EBP ELOVL4 ELOVL7 ERGIC3 FAM210B FCER1G GPR152 KASH5 LAPTM5 LMNA REEP4 RETREG3 RNF24 SCN3B SEC11C SGMS2 SLC10A6 SLC30A8 SNAP23 SNAP29 STX1A STX1B STX4 TMEM101 TMEM14B TMEM35A TMX2 VAPA VAPB	32 interacting genes: ADIPOQ APP BET1 C16orf92 CMTM5 COX20 CTSA CXCL16 CYB5B EHHADH FXYD6 GIMAP1 GOSR2 LNPEP MGLL ORMDL1 RTP2 RUSF1 THBD TMEM106C TMEM120A TMEM14C TMEM201 TMEM222 TMEM229B TMEM243 TMEM42 TRIM55 TRIM63 VAMP1 VAMP3 VAPA
Entrez ID		6843	59353
HPRD ID		01716	06523
Ensembl ID		ENSG00000139190	ENSG00000126950
Uniprot IDs		F5GZV7 P23763	Q53FP2
PDB IDs			9H9E
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane SNAP Receptor Activity Organelle Localization By Membrane Tethering Membrane Docking SNARE Complex Membrane Organization Secretion By Cell Exocytosis Organelle Localization Membrane Fusion Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Signal Release Intracellular Protein Localization Endoplasmic Reticulum Vesicle Fusion To Plasma Membrane Vesicle Fusion Organelle Membrane Fusion Vesicle-mediated Transport Vesicle Organization Synaptic Vesicle Membrane Organization Positive Regulation Of Protein Localization To Cell Surface Organelle Fusion Endoplasmic Reticulum Organization Cellular Localization Establishment Of Localization In Cell FFAT Motif Binding Golgi Vesicle Transport Positive Regulation Of Protein Localization COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Synaptic Vesicle Exocytosis Sphingolipid Biosynthetic Process Cytoplasmic Vesicle Regulated Exocytosis Regulation Of Protein Localization To Cell Surface Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid ATP-dependent Protein Binding Endoplasmic Reticulum Localization Regulation Of Protein Localization Fatty Acid Elongation, Saturated Fatty Acid Protein Binding Presynapse Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of Regulated Secretory Pathway Azurophil Granule Membrane Host-mediated Activation Of Viral Genome Replication	Membrane Membrane Fusion SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Membrane Organization Sphingomyelin Biosynthetic Process SNARE Complex Assembly Cellular Localization Endoplasmic Reticulum Vesicle Organization Positive Regulation Of CAMP/PKA Signal Transduction Response To CAMP Endoplasmic Reticulum Membrane Sphingomyelin Metabolic Process
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