MLLT10 and SS18

Number of citations of the paper that reports this interaction (PMID 11423977)
8

Data Source:
HPRD (two hybrid, in vivo)

		MLLT10	SS18
Gene Name		myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	synovial sarcoma translocation, chromosome 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytoplasmic Microtubule NpBAF Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Microtubule Cytoskeleton Organization Cell Morphogenesis Transcription, DNA-templated Intracellular Signal Transduction Response To Drug Positive Regulation Of Transcription From RNA Polymerase II Promoter Ephrin Receptor Signaling Pathway Neuronal Stem Cell Maintenance
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Meningioma ( 21804547) Ovarian cancer ( 23535730)	Obesity-related traits ( 23251661) Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		7 interactors: DISC1 DOT1L MLLT1 NDEL1 RGPD5 SS18 YEATS4	8 interactors: EP300 GRB2 H3F3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4
Entrez ID		8028	6760
HPRD ID		03874	02559
Ensembl ID		ENSG00000078403	ENSG00000141380
Uniprot IDs		P55197 Q59EQ6 Q6N002	B4DLD3 B4E2J6 Q15532 Q4VAX0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebral Cortex Radially Oriented Cell Migration Microtubule Cytoskeleton Organization Cerebral Cortex Cell Migration Histone H3-K79 Methylation Telencephalon Cell Migration Forebrain Cell Migration Organelle Organization Cerebral Cortex Development Neuron Migration Microtubule-based Process Pallium Development Positive Regulation Of Axon Regeneration Retrograde Axon Cargo Transport Peptidyl-lysine Modification Positive Regulation Of Neuron Projection Regeneration Activation Of Cdc42 GTPase Activity Mitotic Centrosome Separation Telencephalon Development Neurofilament Cytoskeleton Organization Cytoskeleton Organization Centrosome Separation Mitotic Nuclear Division Regulation Of Axon Regeneration Histone H2A Acetylation Positive Regulation Of Cdc42 GTPase Activity Regulation Of Metabolic Process Regulation Of Neuron Projection Development Mitochondrial Calcium Ion Homeostasis Histone Modification Inner Cell Mass Cell Proliferation Positive Regulation Of Neurogenesis Regulation Of Synapse Maturation Neuronal Stem Cell Maintenance Microtubule Nucleation TOR Signaling Forebrain Development Protein Targeting To Golgi Regulation Of Cdc42 GTPase Activity Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Transcription Regulatory Region DNA Binding Blastocyst Growth Microtubule Polymerization Regulation Of Cdc42 Protein Signal Transduction Regulation Of Cell Projection Organization Regulation Of Cell Differentiation Positive Regulation Of Neuroblast Proliferation Centrosome Localization	Aortic Smooth Muscle Cell Differentiation Chromatin Organization Positive Regulation By Host Of Viral Transcription DNA Methylation On Cytosine Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Vascular Smooth Muscle Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway Chromatin Modification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Interaction With Symbiont Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Chromatin Silencing Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Transcription Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Smooth Muscle Cell Differentiation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cell Growth DNA Methylation Positive Regulation Of Metabolic Process Gene Expression Histone Modification Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone H2B Acetylation Transcription, DNA-templated DNA Modification RNA Biosynthetic Process Muscle Structure Development Gene Silencing Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Internal Peptidyl-lysine Acetylation
Tagcloud ?		batch calling classify cooperative driver exome fer filtering fusions h3f3a indels leukemias lmo1 nkx2 normalization normalizations obtaining perturbations pipelines plag1 ptk2b seq skipping snv snvs ssbp2 stat5b tlx1 tpm3	5p algorithms amenable cdkn1a colonies confer conferred fuji hs innovative meanwhile mib mir miranda mirna noteworthy oncomir oncoprotein p21 pictar sarcoma sarcomas ssx succeeded suppressors syii synovial tumorigenicity utr
Tagcloud (Difference) ?		batch calling classify cooperative driver exome fer filtering fusions h3f3a indels leukemias lmo1 nkx2 normalization normalizations obtaining perturbations pipelines plag1 ptk2b seq skipping snv snvs ssbp2 stat5b tlx1 tpm3	5p algorithms amenable cdkn1a colonies confer conferred fuji hs innovative meanwhile mib mir miranda mirna noteworthy oncomir oncoprotein p21 pictar sarcoma sarcomas ssx succeeded suppressors syii synovial tumorigenicity utr
Tagcloud (Intersection) ?