SS18 and RBM14

Number of citations of the paper that reports this interaction (PubMedID 16227627)
0

Data Source:
BioGRID (two hybrid)

		SS18	RBM14
Description		SS18 subunit of BAF chromatin remodeling complex	RNA binding motif protein 14
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Microtubule Cytoskeleton SWI/SNF Complex NpBAF Complex GBAF Complex	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	Nucleic Acid Binding Transcription Coactivator Activity RNA Binding MRNA Binding Protein Binding Splicing Factor Binding
	Biological Process	Microtubule Cytoskeleton Organization Cell Morphogenesis Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Intracellular Signal Transduction Negative Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Neuronal Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Immune System Process Apoptotic Process Gastrulation Response To Hormone Gene Expression Innate Immune Response Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Centriole Replication Centriole Assembly Regulation Of Response To DNA Integrity Checkpoint Signaling
Pathways		Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	RUNX2 regulates bone development
Drugs
Diseases		Synovial sarcoma
GWAS		Autoimmune thyroid disease ( 32581359) Daytime nap ( 33568662) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Mean corpuscular hemoglobin ( 32888494) Nickel levels ( 26025379) Obesity-related traits ( 23251661) Periodontitis (Mean PAL) ( 24024966) QT interval (sulfonylurea treatment interaction) ( 27958378) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Toenail selenium levels ( 25343990)	Bipolar disorder ( 21926972)
Interacting Genes		9 interacting genes: EP300 FUS GRB2 H3-3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4	118 interacting genes: AKAP9 ATN1 CASK CEBPA CEP55 CFTR CRLF3 CTBP1 DDX17 DDX6 DMRTB1 DYNLT1 EP300 FMR1 FXR2 HOMER3 ITCH KHDRBS2 KIFAP3 KLC4 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NCOA6 NDEL1 NEDD4 NFKBID NR3C1 PARD6G PARP1 PCBP1 PRKCI QKI RBM10 RBM5 RPA2 RUNX1 RUNX2 SLAIN1 SS18 SYT1 TARBP2 TRIM55 TRIM63 UBE2I UFSP1 XRCC5 YAP1 YWHAE
Entrez ID		6760	10432
HPRD ID		02559	11485
Ensembl ID		ENSG00000141380	ENSG00000239306
Uniprot IDs		B4DLD3 B4DR34 Q15532 Q4VAX0	A0A0S2Z4Z0 A0A0S2Z567 A0A0S2Z5V2 Q96PK6
PDB IDs		7VRB	2DNP
Enriched GO Terms of Interacting Partners?		Epigenetic Regulation Of Gene Expression Transcription Coactivator Activity Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Leukocyte Differentiation Positive Regulation Of Cell Adhesion Transcription Initiation-coupled Chromatin Remodeling Regulation Of T Cell Differentiation Chromatin Binding Regulation Of Cell-cell Adhesion Nucleosome Array Spacer Activity Regulation Of Lymphocyte Activation Positive Regulation Of Immune System Process Regulation Of Lymphocyte Differentiation Regulation Of Organelle Organization Regulation Of Cell Activation Chromatin Remodeling BBAF Complex Positive Regulation Of Double-strand Break Repair Positive Regulation Of T-helper 17 Cell Differentiation NpBAF Complex GBAF Complex Regulation Of Cell Adhesion Chromatin Organization NBAF Complex Host-mediated Activation Of Viral Transcription Regulation Of Immune System Process Activation Of Immune Response Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Hemopoiesis Positive Regulation Of DNA Repair Heterochromatin Formation Positive Regulation Of Cell Development Regulation Of Double-strand Break Repair Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Histone Binding Nuclear Androgen Receptor Binding Positive Regulation Of T-helper Cell Differentiation	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process MRNA Destabilization Regulation Of Metabolic Process Positive Regulation Of MRNA Catabolic Process RNA Destabilization Negative Regulation Of Cytokine Production Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Translation Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Developmental Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Development Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Signal Transduction Regulation Of Multicellular Organismal Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Blood Vessel Endothelial Cell Migration
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