MLLT10

Gene Name		myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Meningioma ( 21804547) Ovarian cancer ( 23535730)
Protein-protein Interactions		7 interactors: DISC1 DOT1L MLLT1 NDEL1 RGPD5 SS18 YEATS4
Entrez ID		8028
HPRD ID		03874
Ensembl ID		ENSG00000078403
Uniprot IDs		P55197 Q59EQ6 Q6N002
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebral Cortex Radially Oriented Cell Migration Microtubule Cytoskeleton Organization Cerebral Cortex Cell Migration Histone H3-K79 Methylation Telencephalon Cell Migration Forebrain Cell Migration Organelle Organization Cerebral Cortex Development Neuron Migration Microtubule-based Process Pallium Development Positive Regulation Of Axon Regeneration Retrograde Axon Cargo Transport Peptidyl-lysine Modification Positive Regulation Of Neuron Projection Regeneration Activation Of Cdc42 GTPase Activity Mitotic Centrosome Separation Telencephalon Development Neurofilament Cytoskeleton Organization Cytoskeleton Organization Centrosome Separation Mitotic Nuclear Division Regulation Of Axon Regeneration Histone H2A Acetylation Positive Regulation Of Cdc42 GTPase Activity Regulation Of Metabolic Process Regulation Of Neuron Projection Development Mitochondrial Calcium Ion Homeostasis Histone Modification Inner Cell Mass Cell Proliferation Positive Regulation Of Neurogenesis Regulation Of Synapse Maturation Neuronal Stem Cell Maintenance Microtubule Nucleation TOR Signaling Forebrain Development Protein Targeting To Golgi Regulation Of Cdc42 GTPase Activity Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Transcription Regulatory Region DNA Binding Blastocyst Growth Microtubule Polymerization Regulation Of Cdc42 Protein Signal Transduction Regulation Of Cell Projection Organization Regulation Of Cell Differentiation Positive Regulation Of Neuroblast Proliferation Centrosome Localization See more
Tagcloud ?		batch calling classify cooperative driver exome fer filtering fusions h3f3a indels leukemias lmo1 nkx2 normalization normalizations obtaining perturbations pipelines plag1 ptk2b seq skipping snv snvs ssbp2 stat5b tlx1 tpm3