SS18 and SMARCA2

Number of citations of the paper that reports this interaction (PMID 11734557)
26

Data Source:
HPRD (in vitro, in vivo)

		SS18	SMARCA2
Gene Name		synovial sarcoma translocation, chromosome 18	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasmic Microtubule NpBAF Complex	Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton NpBAF Complex NBAF Complex
	Molecular Function	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity	RNA Polymerase II Transcription Coactivator Activity Transcription Coactivator Activity Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity Histone Binding Transcription Regulatory Region DNA Binding
	Biological Process	Microtubule Cytoskeleton Organization Cell Morphogenesis Transcription, DNA-templated Intracellular Signal Transduction Response To Drug Positive Regulation Of Transcription From RNA Polymerase II Promoter Ephrin Receptor Signaling Pathway Neuronal Stem Cell Maintenance	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Growth Aortic Smooth Muscle Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Rhegmatogenous retinal detachment ( 23585552)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions		8 interactors: EP300 GRB2 H3F3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4	26 interactors: ACTL6A ACTL6B AR ARID1B BEND7 BRCA1 CEBPA DPF3 ESR1 HIST1H3A KHDRBS1 MDM2 MDM4 MECP2 MYB MYC NR0B2 NR3C1 NR4A2 PHB PITX1 PRMT5 PRPF6 SDCBP SIN3B SS18
Entrez ID		6760	6595
HPRD ID		02559	02483
Ensembl ID		ENSG00000141380	ENSG00000080503
Uniprot IDs		B4DLD3 B4E2J6 Q15532 Q4VAX0	P51531 Q56A76 Q8N9Q1
PDB IDs			2DAT
Enriched GO Terms of Interacting Partners?		Aortic Smooth Muscle Cell Differentiation Chromatin Organization Positive Regulation By Host Of Viral Transcription DNA Methylation On Cytosine Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Vascular Smooth Muscle Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway Chromatin Modification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Interaction With Symbiont Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Chromatin Silencing Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Transcription Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Smooth Muscle Cell Differentiation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cell Growth DNA Methylation Positive Regulation Of Metabolic Process Gene Expression Histone Modification Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone H2B Acetylation Transcription, DNA-templated DNA Modification RNA Biosynthetic Process Muscle Structure Development Gene Silencing Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Internal Peptidyl-lysine Acetylation	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Chromatin Organization RNA Metabolic Process Chromatin Modification Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Chromosome Organization Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Organelle Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Cyclic Compound Intracellular Steroid Hormone Receptor Signaling Pathway Response To Steroid Hormone Cellular Response To Steroid Hormone Stimulus Transcription Initiation From RNA Polymerase II Promoter Chromatin Remodeling Developmental Process Negative Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Cellular Process Steroid Hormone Mediated Signaling Pathway Anatomical Structure Development
Tagcloud ?		5p algorithms amenable cdkn1a colonies confer conferred fuji hs innovative meanwhile mib mir miranda mirna noteworthy oncomir oncoprotein p21 pictar sarcoma sarcomas ssx succeeded suppressors syii synovial tumorigenicity utr	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Difference) ?		5p algorithms amenable cdkn1a colonies confer conferred fuji hs innovative meanwhile mib mir miranda mirna noteworthy oncomir oncoprotein p21 pictar sarcoma sarcomas ssx succeeded suppressors syii synovial tumorigenicity utr	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Intersection) ?