ATOSB and PDLIM7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATOSB	PDLIM7
Description		atos homolog B	PDZ and LIM domain 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Stress Fiber Ruffle Nucleoplasm Cytoplasm Cytosol Cytoskeleton Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin
	Molecular Function	Protein Binding	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process		Ossification Receptor-mediated Endocytosis Heart Development Actin Cytoskeleton Organization Cell Differentiation Muscle Structure Development
Pathways			RET signaling
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		64 interacting genes: ABI2 AKAP8L APP BAG4 C11orf65 C7orf57 CALCOCO2 CCDC125 CCDC33 CCDC85B CEP70 CFTR CYSRT1 DIP2A DNAJA3 EFHC2 EYA2 FHL2 FHL5 GOLGA2 GPRASP3 HSF2BP HSPB8 IKZF1 KIF20A KPNA3 KPNA5 KRT34 KRTAP19-5 KRTAP19-6 KRTAP6-2 KRTAP6-3 LMO2 LZTS2 MDFI MID2 MKRN3 MYO1F MYO5B MYOZ3 NCOA5 PDLIM7 PFDN5 PICK1 PRDM6 PTPN21 RBM11 SFMBT1 SLAIN1 SORBS3 TBC1D23 TEPSIN TLE5 TRAF2 TRAF4 TRIM27 VPS9D1 WWOX WWP2 ZMYND12 ZNF219 ZNF572 ZNF655 ZRANB1	63 interacting genes: ABI2 AP5B1 ATOSB BAG3 BSG CATSPER1 CCDC185 DDX6 DGCR6 DNER ENKD1 FAM90A1 FNDC11 FRS3 GARIN6 GEM GFAP GPATCH2L HEY2 HNRNPD HNRNPF HSF2BP HSPB7 IL16 IQGAP1 KANK2 MDM2 NUDT10 OTUD6A PAK5 PARVG PCBP1 PHF1 PIN1 PLEKHN1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RASGEF1B RET RPP25 SCNM1 SH2B2 SH3BP2 SLAIN1 SMURF1 SNCA SPP1 TCF19 TNPO2 TP53 TPM2 TRAF2 TRAF3 TSG101 TSGA10IP UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		80256	9260
HPRD ID		13869	10436
Ensembl ID		ENSG00000005238	ENSG00000196923
Uniprot IDs		Q7L5A3	Q9NR12
PDB IDs			2Q3G 7RM8
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Negative Regulation Of RNA Metabolic Process Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Cytoplasm Cytoskeleton Regulation Of Supramolecular Fiber Organization Cytosol Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Targeting To Mitochondrion Regulation Of Actin Nucleation Intermediate Filament Regulation Of RNA Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Neuron Projection Organization Zinc Ion Binding NLS-dependent Protein Nuclear Import Complex Positive Regulation Of Cytoskeleton Organization Thioesterase Binding	Protein Binding Diacylglycerol-dependent Serine/threonine Kinase Activity Histone H3T6 Kinase Activity Striated Muscle Cell Apoptotic Process Cellular Response To Actinomycin D Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Muscle Cell Apoptotic Process Response To Actinomycin D Protein Kinase C Signaling Cellular Response To UV-C Regulation Of MAPK Cascade Signaling Adaptor Activity Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Transport Regulation Of Protein Metabolic Process Regulation Of Chaperone-mediated Autophagy Regulation Of Programmed Cell Death Histone H3K36me3 Reader Activity Actin Filament Apoptotic Process Regulation Of Gene Expression Cytoplasmic Side Of Plasma Membrane Supramolecular Fiber Organization Negative Regulation Of Catabolic Process Enzyme Binding Programmed Cell Death Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Cellular Response To Antibiotic Cell Death Negative Regulation Of Programmed Cell Death Mitotic Nuclear Membrane Disassembly Negative Regulation Of Glial Cell Apoptotic Process Thioesterase Binding CD40 Receptor Complex
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