ATOSB and MYO5B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATOSB	MYO5B
Description		atos homolog B	myosin VB
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Actin Cytoskeleton Membrane Myosin Complex Cytoplasmic Vesicle Membrane Protein-containing Complex Apical Cortex Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Small GTPase Binding Actin Filament Binding
	Biological Process		Renal Water Homeostasis Endocytosis Actin Filament Organization Protein Transport Vesicle-mediated Transport Endosomal Transport
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 29084231 32203549) HDL cholesterol levels ( 32203549) Large HDL particle concentration ( 29084231) Longevity (100 years and older) ( 33948810) Mean diameter of HDL particles ( 29084231) Medium HDL particle concentration ( 29084231) Multiple sclerosis ( 31604244) Myopia ( 27182965) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231) Refractive error ( 32231278) Resistant hypertension ( 31545351) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Total cholesterol levels in HDL ( 29084231)
Interacting Genes		64 interacting genes: ABI2 AKAP8L APP BAG4 C11orf65 C7orf57 CALCOCO2 CCDC125 CCDC33 CCDC85B CEP70 CFTR CYSRT1 DIP2A DNAJA3 EFHC2 EYA2 FHL2 FHL5 GOLGA2 GPRASP3 HSF2BP HSPB8 IKZF1 KIF20A KPNA3 KPNA5 KRT34 KRTAP19-5 KRTAP19-6 KRTAP6-2 KRTAP6-3 LMO2 LZTS2 MDFI MID2 MKRN3 MYO1F MYO5B MYOZ3 NCOA5 PDLIM7 PFDN5 PICK1 PRDM6 PTPN21 RBM11 SFMBT1 SLAIN1 SORBS3 TBC1D23 TEPSIN TLE5 TRAF2 TRAF4 TRIM27 VPS9D1 WWOX WWP2 ZMYND12 ZNF219 ZNF572 ZNF655 ZRANB1	23 interacting genes: AMOTL2 ATOSB BNIP2 COIL CXCR2 EFHC2 FXR1 GMCL1 KIAA1549 MEI4 MEOX2 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 SHANK3 SMAD3 SMARCA2 TCF4 TRIM3 TRIM54 ZNHIT1
Entrez ID		80256	4645
HPRD ID		13869	07582
Ensembl ID		ENSG00000005238	ENSG00000167306
Uniprot IDs		Q7L5A3	Q7Z7A5 Q9ULV0
PDB IDs			4J5M 4LNZ 4LWZ 4LX0
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Negative Regulation Of RNA Metabolic Process Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Cytoplasm Cytoskeleton Regulation Of Supramolecular Fiber Organization Cytosol Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Targeting To Mitochondrion Regulation Of Actin Nucleation Intermediate Filament Regulation Of RNA Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Neuron Projection Organization Zinc Ion Binding NLS-dependent Protein Nuclear Import Complex Positive Regulation Of Cytoskeleton Organization Thioesterase Binding	Myosin V Binding Regulation Of Long-term Neuronal Synaptic Plasticity Recycling Endosome Amyloid-beta Clearance By Transcytosis Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Cell Differentiation Germ Cell Development G Protein Activity Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cell Projection Exocytosis Transcytosis Regulation Of Endocytic Recycling Recycling Endosome Membrane Establishment Of Melanosome Localization Melanosome Localization Melanosome Transport Pigment Granule Transport Pigment Granule Localization Amyloid-beta Clearance Epithelial Cell Morphogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?