FAM214B and DNAJA3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM214B	DNAJA3
Gene Name		family with sequence similarity 214, member B	DnaJ (Hsp40) homolog, subfamily A, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Actin Filament IkappaB Kinase Complex Extrinsic Component Of Plasma Membrane Cell Junction Neuromuscular Junction I-kappaB/NF-kappaB Complex Mitochondrial Nucleoid Intracellular Membrane-bounded Organelle Postsynaptic Membrane
	Molecular Function		Small GTPase Regulator Activity Interferon-gamma Receptor Binding Protein Binding ATP Binding Transcription Factor Binding Protein Kinase Binding Hsp70 Protein Binding Receptor Tyrosine Kinase Binding Metal Ion Binding NF-kappaB Binding Unfolded Protein Binding Chaperone Binding
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitochondrial DNA Replication Protein Folding Negative Regulation Of Protein Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Neuromuscular Junction Development Cell Aging Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity T Cell Differentiation In Thymus Response To Interferon-gamma Protein Refolding Positive Regulation Of T Cell Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Catalytic Activity Protein Stabilization Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP CCDC85B CEP70 DIP2A DNAJA3 IKZF1 KIF20A TRIM27	38 interactors: ALS2CR11 ATXN1 BRCA1 CARM1 COIL FAM131C FAM214B FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 HSPA9 IFNGR2 INPP5J JAK2 KDM1A KRAS MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 RAD51 RASA1 RELA RNF34 SMAD9 STK16 TCF19 USP7 VHL ZBTB22
Entrez ID		80256	9093
HPRD ID		13869	09758
Ensembl ID		ENSG00000005238	ENSG00000103423
Uniprot IDs		Q7L5A3	B3KM81 E7ES32 Q53G26 Q59E88 Q96EY1
PDB IDs			2CTT 2DN9
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Neuromuscular Junction Development Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Multicellular Organism Growth Negative Regulation Of Biosynthetic Process Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Immune Response Regulation Of Growth Collateral Sprouting In Absence Of Injury Positive Regulation Of Peptidase Activity T Cell Differentiation Cell Activation Synapse Organization Regulation Of Gene Expression Regulation Of Protein Kinase Activity Collateral Sprouting Axon Midline Choice Point Recognition Organelle Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of T Cell Activation Axon Choice Point Recognition Positive Regulation Of NK T Cell Differentiation Activation-induced Cell Death Of T Cells Negative Regulation Of Protein Kinase Activity Positive Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of Protein Metabolic Process Negative Regulation Of Kinase Activity Lymphocyte Differentiation Interferon-gamma Secretion Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Cell-cell Adhesion Neuron Remodeling Negative Regulation Of Endopeptidase Activity Skeletal Muscle Acetylcholine-gated Channel Clustering Immune System Process Negative Regulation Of Peptidase Activity T Cell Aggregation	Response To Abiotic Stimulus Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Apoptotic Process Response To Organic Substance Response To Organonitrogen Compound Response To Stress Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Cellular Process Cellular Response To Stress Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Viral Process Positive Regulation Of NF-kappaB Transcription Factor Activity Transcription, DNA-templated Regulation Of Signaling RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Histone H3-R2 Methylation Response To Organic Cyclic Compound Response To Radiation Regulation Of Histone H3-K4 Methylation Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation Cellular Response To Organonitrogen Compound Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Stimulus Response To Temperature Stimulus
Tagcloud ?			acted adenocarcinoma allylamino causing cochaperone colony concluded conversely counteracting counterparts demethoxy differently egfr enhancing geldanamycin hsp70 hsp90 interacted inversely isoforms oncogenic orthotropic proteasomal restored subcutaneous tid1 ubiquitinylation xenograft
Tagcloud (Difference) ?			acted adenocarcinoma allylamino causing cochaperone colony concluded conversely counteracting counterparts demethoxy differently egfr enhancing geldanamycin hsp70 hsp90 interacted inversely isoforms oncogenic orthotropic proteasomal restored subcutaneous tid1 ubiquitinylation xenograft
Tagcloud (Intersection) ?