DBF4B and KRTAP4-12

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		DBF4B	KRTAP4-12
Gene Name		DBF4 zinc finger B	keratin associated protein 4-12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Aggresome Intracellular Membrane-bounded Organelle	Keratin Filament
	Molecular Function	Nucleic Acid Binding Zinc Ion Binding Protein Kinase Binding Protein Kinase Activator Activity	Protein Binding
	Biological Process	Cell Cycle Positive Regulation Of Cell Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Kinase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CDC7 KDM1A KRTAP4-12 LMO2 MDFI SRPK2 SUV39H1	107 interactors: ADAMTSL4 ALPP AQP1 ATG12 ATN1 BAHD1 BEX2 C10orf62 C19orf66 CATSPER1 CBX2 CCDC116 CCDC185 CCNK CDC42EP1 CHCHD3 CHIC2 CLDN2 CNNM3 CNTFR COL8A1 CRCT1 CREB5 CRY1 DBF4B DLK2 EIF4E2 FAM107A FAM27E3 FAM76B FBXL18 FBXW5 GLRX3 GNE GPATCH2L GPRIN2 GRAP2 HHEX HOXA1 HOXB9 IFI30 ILF3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2D LCE3E LCE4A LINGO1 LNX1 MAPKBP1 MEOX2 MRPL4 NOTCH2NL NPDC1 NUDT18 NUFIP2 OTX1 PCSK5 PDGFRB PFKL PHLDA1 PLSCR1 PLSCR4 PNKP PRKAB2 PRR13 QPRT RERE RPS28 SLC25A10 SLC25A6 SMCP SPATA3 SPG7 SPRY2 TAP1 TBC1D16 TBC1D23 TCEB3B THAP10 THAP7 TOP3B TXNDC5 ZBTB16 ZNF165 ZNF20 ZNF250 ZNF408 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF581 ZNF638 ZNF655 ZNF764 ZSCAN26
Entrez ID		80174	83755
HPRD ID		16840	13941
Ensembl ID		ENSG00000161692	ENSG00000213416
Uniprot IDs		Q8NFT6	Q9BQ66
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Erythrocyte Differentiation Negative Regulation Of DNA Binding Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Negative Regulation Of Binding Nuclear Speck Organization Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Metabolic Process Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Double-strand Break Repair Via Break-induced Replication Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Regulation Of Myeloid Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Histone H3-K9 Dimethylation Regulation Of Binding Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Positive Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Regulation Of Nuclear Cell Cycle DNA Replication Ribonucleoprotein Complex Biogenesis Histone H3-K9 Trimethylation Cellular Response To Thyroid Hormone Stimulus Positive Regulation Of Hormone Biosynthetic Process Peptidyl-lysine Dimethylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process MRNA Transcription From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Developmental Process Nitrogen Compound Metabolic Process	Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Transcription, DNA-templated Biosynthetic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Keratinization Anterior/posterior Pattern Specification Regulation Of Cellular Process Regulation Of Metabolic Process Cellular Process Keratinocyte Differentiation Embryo Development Phospholipid Scrambling Metanephric Glomerulus Vasculature Development Pattern Specification Process Metanephric Glomerulus Development Epidermal Cell Differentiation Epidermis Development Mitochondrion Organization Metabolic Process Forebrain Morphogenesis Transcription From RNA Polymerase II Promoter Glomerulus Vasculature Development Multicellular Organismal Development Organic Anion Transport Inner Ear Development Cell Migration Involved In Coronary Angiogenesis Hepatic Duct Development Abducens Nerve Formation Metanephric Mesenchymal Cell Migration Transepithelial Water Transport Renin Secretion Into Blood Stream Metanephric Descending Thin Limb Development DGDP Catabolic Process Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development
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