DBF4B

Description		DBF4B-CDC7 kinase regulatory subunit
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Dbf4-dependent Protein Kinase Complex
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		17 interacting genes: CDC7 CYSRT1 GEM HEXIM2 HOXA1 KDM1A KRTAP4-12 LMO2 LRRK2 MDFI PCSK5 ROPN1 SGF29 SRPK2 SUV39H1 TRIM27 ZNF655
Entrez ID		80174
HPRD ID		16840
Ensembl ID		ENSG00000161692
Uniprot IDs		Q8NFT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Mitotic Spindle Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Epigenetic Regulation Of Gene Expression Regulation Of Cell Cycle Magnesium Ion Binding Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Semicircular Canal Formation Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Abducens Nerve Formation Optokinetic Behavior Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Chromatin Organization Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Determination Of Adult Lifespan Regulation Of DNA Repair Regulation Of Neuroblast Proliferation Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly
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