DBF4B and CDC7

Number of citations of the paper that reports this interaction (PMID 12065429)
19

Data Source:
HPRD (in vivo, in vitro)

		DBF4B	CDC7
Gene Name		DBF4 zinc finger B	cell division cycle 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Aggresome Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Nucleic Acid Binding Zinc Ion Binding Protein Kinase Binding Protein Kinase Activator Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding
	Biological Process	Cell Cycle Positive Regulation Of Cell Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Kinase Activity	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Replication Initiation Phagocytosis Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Cell Cycle Phase Transition Cell Division
Pathways			G1/S Transition G2/M Checkpoints Activation of ATR in response to replication stress Activation of the pre-replicative complex DNA Replication Pre-Initiation M/G1 Transition Cell Cycle Checkpoints Activation of the pre-replicative complex Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Optic disc parameters ( 20548946 21307088)
Protein-Protein Interactions		7 interactors: CDC7 KDM1A KRTAP4-12 LMO2 MDFI SRPK2 SUV39H1	24 interactors: APP CDK2 CDK4 CDK9 CDKN1A CDKN2A CHAF1A CLSPN DBF4 DBF4B DIAPH1 GPT GRHPR MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC5 ORC6 TOB1
Entrez ID		80174	8317
HPRD ID		16840	10345
Ensembl ID		ENSG00000161692	ENSG00000097046
Uniprot IDs		Q8NFT6	B2R6V2 J3KQS2 O00311
PDB IDs			4F99 4F9A 4F9B 4F9C
Enriched GO Terms of Interacting Partners?		Regulation Of Erythrocyte Differentiation Negative Regulation Of DNA Binding Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Negative Regulation Of Binding Nuclear Speck Organization Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Metabolic Process Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Double-strand Break Repair Via Break-induced Replication Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Regulation Of Myeloid Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Histone H3-K9 Dimethylation Regulation Of Binding Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Positive Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Regulation Of Nuclear Cell Cycle DNA Replication Ribonucleoprotein Complex Biogenesis Histone H3-K9 Trimethylation Cellular Response To Thyroid Hormone Stimulus Positive Regulation Of Hormone Biosynthetic Process Peptidyl-lysine Dimethylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process MRNA Transcription From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Developmental Process Nitrogen Compound Metabolic Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Replication Initiation DNA-dependent DNA Replication Cell Cycle Cell Cycle Process DNA Metabolic Process DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Duplex Unwinding DNA Geometric Change DNA Unwinding Involved In DNA Replication DNA Conformation Change Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Cell Cycle Process Chromosome Organization Macromolecule Biosynthetic Process Regulation Of Cell Cycle Arrest Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Biosynthetic Process Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Phosphorylation Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Arrest Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Cellular Response To Stress Organelle Organization Regulation Of Kinase Activity
Tagcloud ?			af ana antinuclear assignment beads blots cdc10 cdc2 cdc4 cdc5 cdc9 dilutions foundation immunodiffusion intensities jo monospecific originally purposes reagents reference rnp ro semiquantitative sera ss u1 weaker
Tagcloud (Difference) ?			af ana antinuclear assignment beads blots cdc10 cdc2 cdc4 cdc5 cdc9 dilutions foundation immunodiffusion intensities jo monospecific originally purposes reagents reference rnp ro semiquantitative sera ss u1 weaker
Tagcloud (Intersection) ?