TRAPPC13 and PEA15

Number of citations of the paper that reports this interaction (PubMedID 24710276)
50

Data Source:
BioGRID (two hybrid)

		TRAPPC13	PEA15
Description		trafficking protein particle complex subunit 13	proliferation and apoptosis adaptor protein 15
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol TRAPPII Protein Complex TRAPPIII Protein Complex	Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Vesicle Tethering	MAPK Cascade Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of D-glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		RAB GEFs exchange GTP for GDP on RABs	RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: PEA15 SYCE1L	40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13
Entrez ID		80006	8682
HPRD ID		07832	04579
Ensembl ID		ENSG00000113597	ENSG00000162734
Uniprot IDs		A5PLN9	B1AKZ4 B1AKZ5 Q15121 Q96FS5
PDB IDs			4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?			Insulin-like Growth Factor Receptor Signaling Pathway Protein Serine Kinase Activity Cytosol Cytoplasm Protein Serine/threonine Kinase Activity Response To Epidermal Growth Factor Positive Regulation Of Macrophage Differentiation Regulation Of Golgi Organization Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Execution Phase Of Apoptosis Interleukin-34-mediated Signaling Pathway Protein Kinase Activity ERBB Signaling Pathway Phosphate-containing Compound Metabolic Process Positive Regulation Of Cell Migration Response To Peptide Response To Cytokine Regulation Of Cellular Response To Stress Negative Regulation Of Programmed Cell Death Insulin Receptor Signaling Pathway Execution Phase Of Apoptosis Death Effector Domain Binding Regulation Of Macrophage Differentiation Regulation Of Golgi Inheritance Neural Crest Cell Development ATP Binding Positive Regulation Of Cell Motility Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Positive Regulation Of Locomotion Stem Cell Development Ripoptosome CD95 Death-inducing Signaling Complex Phospholipase D Activity Lipopolysaccharide-mediated Signaling Pathway RNA (guanine-N7)-methylation Death-inducing Signaling Complex Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Regulation Of Telomere Maintenance Regulation Of DNA Metabolic Process Negative Regulation Of Apoptotic Process Protein Phosphorylation Protein Autophosphorylation Response To Tumor Necrosis Factor Vascular Endothelial Cell Response To Laminar Fluid Shear Stress TRAIL-activated Apoptotic Signaling Pathway Outer Ear Morphogenesis ERBB3 Signaling Pathway
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