KAT6A and MAFK

Number of citations of the paper that reports this interaction (PMID 17083329)
9

Data Source:
BioGRID (affinity chromatography technology, pull down)

		KAT6A	MAFK
Gene Name		K(lysine) acetyltransferase 6A	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Nucleolus Golgi Apparatus PML Body MOZ/MORF Histone Acetyltransferase Complex	Nucleoplasm
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Acetyltransferase Activity	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Cofactor Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Heart Morphogenesis DNA Packaging Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Protein Acetylation Histone Acetylation Myeloid Cell Differentiation Somatic Stem Cell Maintenance Embryonic Hemopoiesis Aorta Morphogenesis Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Face Morphogenesis Cellular Senescence	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Blood Coagulation
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKT1 ATN1 ATXN1 CREBBP H3F3C HIST1H3A HIST1H4A HIST1H4I HIST2H3C HIST3H3 HIST4H4 MAFK PML RERE RUNX1 SPI1 TP53 UBE2U	10 interactors: BACH1 BACH2 HIF1A HOXD12 KAT6A MARS NFE2 NFE2L1 NFE2L2 NFE2L3
Entrez ID		7994	7975
HPRD ID		03244	02561
Ensembl ID		ENSG00000083168	ENSG00000198517
Uniprot IDs		A5PKX7 Q92794	A4D214 O60675
PDB IDs		1M36 2LN0 2OZU 2RC4 3V43
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromatin Silencing At RDNA Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Chromatin Silencing Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication-dependent Nucleosome Assembly Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Chromosome Organization Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process Histone H4-K20 Demethylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process DNA Modification Regulation Of RNA Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Megakaryocyte Differentiation Gene Silencing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Chromatin Assembly Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Chromatin Assembly Or Disassembly Chromatin Modification Regulation Of Myeloid Cell Differentiation DNA Packaging Organelle Organization Histone Modification Telomere Maintenance DNA Metabolic Process Regulation Of Megakaryocyte Differentiation Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Cell Differentiation Regulation Of Cell Differentiation Nucleocytoplasmic Transport CENP-A Containing Nucleosome Assembly Nuclear Transport DNA Conformation Change Protein Import Into Nucleus	RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Cell Death Embryonic Hemopoiesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Regulation Of Cellular Response To Oxidative Stress Cellular Response To Stress Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Bone Mineralization Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Neural Fold Elevation Formation Negative Regulation Of Ossification Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Oxidative Stress Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Tagcloud ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations	abolishment antisense augmented clarify derivative e2 evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers p45 polyploidization prominant shift tal thrombopoietin tpo unclarified
Tagcloud (Difference) ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations	abolishment antisense augmented clarify derivative e2 evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers p45 polyploidization prominant shift tal thrombopoietin tpo unclarified
Tagcloud (Intersection) ?