MAFK and NFE2L1

Number of citations of the paper that reports this interaction (PMID 12805554)
98

Data Source:
HPRD (in vitro)

		MAFK	NFE2L1
Gene Name		v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	nuclear factor, erythroid 2-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Cofactor Binding Sequence-specific DNA Binding Transcription Factor Activity	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Blood Coagulation	Transcription From RNA Polymerase II Promoter Heme Biosynthetic Process Inflammatory Response Anatomical Structure Morphogenesis Erythrocyte Differentiation Cellular Response To Oxidative Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		10 interactors: BACH1 BACH2 HIF1A HOXD12 KAT6A MARS NFE2 NFE2L1 NFE2L2 NFE2L3	14 interactors: ATF4 BACH2 CAPN1 CD6 CREBZF GSK3B HCFC1 JUN JUNB JUND MAFF MAFG MAFK NFE2L3
Entrez ID		7975	4779
HPRD ID		02561	01223
Ensembl ID		ENSG00000198517	ENSG00000082641
Uniprot IDs		A4D214 O60675	B4DYE1 F5H1B7 J3QKY3 J9JIE5 Q14494 Q8NF22
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Cell Death Embryonic Hemopoiesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Regulation Of Cellular Response To Oxidative Stress Cellular Response To Stress Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Bone Mineralization Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Neural Fold Elevation Formation Negative Regulation Of Ossification Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Oxidative Stress Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Circadian Rhythm Cellular Response To Calcium Ion Negative Regulation Of Biosynthetic Process Biosynthetic Process Response To Mechanical Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Rhythmic Process Negative Regulation Of RNA Biosynthetic Process Response To Metal Ion Response To Calcium Ion Regulation Of Metabolic Process Cellular Response To Metal Ion Positive Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Differentiation Cellular Response To Inorganic Substance Negative Regulation Of Cellular Metabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Macromolecule Biosynthetic Process Response To Inorganic Substance Positive Regulation Of Gene Expression Cellular Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Epidermal Cell Differentiation Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Wounding Positive Regulation Of Neuron Apoptotic Process
Tagcloud ?		abolishment antisense augmented clarify derivative e2 evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers p45 polyploidization prominant shift tal thrombopoietin tpo unclarified	11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine p45 seen sequence shows similar similarity subunit zipper
Tagcloud (Difference) ?		abolishment antisense augmented clarify derivative evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers polyploidization prominant shift tal thrombopoietin tpo unclarified	11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine seen sequence shows similar similarity subunit zipper
Tagcloud (Intersection) ?		e2 p45