MAFK and BACH2

Number of citations of the paper that reports this interaction (PMID 8887638)
99

Data Source:
HPRD (in vitro, two hybrid)

		MAFK	BACH2
Gene Name		v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	BTB and CNC homology 1, basic leucine zipper transcription factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus Cytoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Cofactor Binding Sequence-specific DNA Binding Transcription Factor Activity	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Blood Coagulation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Celiac disease ( 20190752) Cognitive performance ( 20125193) Crohn's disease ( 21102463) Graves' disease ( 21841780) IgG glycosylation ( 23382691) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 23273568) Type 1 diabetes ( 19430480 18840781 18978792) Type 1 diabetes autoantibodies ( 21829393) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 22561518)
Protein-Protein Interactions		10 interactors: BACH1 BACH2 HIF1A HOXD12 KAT6A MARS NFE2 NFE2L1 NFE2L2 NFE2L3	8 interactors: BATF3 DDIT3 MAFF MAFG MAFK NFE2L1 NFE2L3 PATZ1
Entrez ID		7975	60468
HPRD ID		02561	12012
Ensembl ID		ENSG00000198517	ENSG00000112182
Uniprot IDs		A4D214 O60675	Q9BYV9
PDB IDs			3OHU 3OHV
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Cell Death Embryonic Hemopoiesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Regulation Of Cellular Response To Oxidative Stress Cellular Response To Stress Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Bone Mineralization Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Neural Fold Elevation Formation Negative Regulation Of Ossification Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Oxidative Stress Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Regulation Of Epidermal Cell Differentiation Regulation Of Metabolic Process Anatomical Structure Development Regulation Of Epidermis Development Developmental Process Negative Regulation Of Transcription, DNA-templated Blood Coagulation Negative Regulation Of Nucleic Acid-templated Transcription Hemostasis Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Gene Expression System Development Negative Regulation Of Biosynthetic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Body Fluid Levels Wound Healing Hemopoiesis Regulation Of Epithelial Cell Differentiation Cellular Metabolic Process Response To Wounding Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Transcription From RNA Polymerase II Promoter Response To Stress Myeloid Cell Differentiation ER Overload Response Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process MRNA Transcription From RNA Polymerase II Promoter
Tagcloud ?		abolishment antisense augmented clarify derivative e2 evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers p45 polyploidization prominant shift tal thrombopoietin tpo unclarified	architectural architecture bach1 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper
Tagcloud (Difference) ?		abolishment antisense augmented clarify derivative e2 evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers p45 polyploidization prominant shift tal thrombopoietin tpo unclarified	architectural architecture bach1 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper
Tagcloud (Intersection) ?		mafk