MAFK and NFE2L3

Number of citations of the paper that reports this interaction (PMID 10037736)
50

Data Source:
HPRD (in vitro, two hybrid)

		MAFK	NFE2L3
Gene Name		v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	nuclear factor, erythroid 2-like 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Cofactor Binding Sequence-specific DNA Binding Transcription Factor Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Blood Coagulation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Body mass index ( 23583978) Obesity-related traits ( 23251661) Waist-hip ratio ( 20935629)
Protein-Protein Interactions		10 interactors: BACH1 BACH2 HIF1A HOXD12 KAT6A MARS NFE2 NFE2L1 NFE2L2 NFE2L3	9 interactors: BACH2 CREB3 MAFF MAFG MAFK NFE2 NFE2L1 NFE2L2 PPARG
Entrez ID		7975	9603
HPRD ID		02561	09162
Ensembl ID		ENSG00000198517	ENSG00000050344
Uniprot IDs		A4D214 O60675	Q9Y4A8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Cell Death Embryonic Hemopoiesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Regulation Of Cellular Response To Oxidative Stress Cellular Response To Stress Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Bone Mineralization Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Neural Fold Elevation Formation Negative Regulation Of Ossification Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Oxidative Stress Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Nitrogen Compound Metabolic Process Blood Coagulation Hemostasis Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Response To Wounding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Epidermal Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermis Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Metformin Response To Diuretic Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Negative Regulation Of Pancreatic Stellate Cell Proliferation Cellular Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Negative Regulation Of Intrinsic Apoptotic Signaling Pathway ER-nucleus Signaling Pathway In Utero Embryonic Development Cellular Response To Topologically Incorrect Protein Cellular Response To Vitamin E Regulation Of Cholesterol Transporter Activity Release From Viral Latency
Tagcloud ?		abolishment antisense augmented clarify derivative e2 evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers p45 polyploidization prominant shift tal thrombopoietin tpo unclarified	ago attracted basic biology bzip cap carcinogenesis cinderella cnc collar come contrary erythroid extensively fascinating homolog importantly insights leucine linking nevertheless newer nrf2 nrf3 overview shed subcellular zipper
Tagcloud (Difference) ?		abolishment antisense augmented clarify derivative e2 evi gata gel glycoprotein gp ib incubation indolocarbasole k252a meg megakaryoblastic megakaryocyte megakaryocytic mpl oligomers p45 polyploidization prominant shift tal thrombopoietin tpo unclarified	ago attracted basic biology bzip cap carcinogenesis cinderella cnc collar come contrary erythroid extensively fascinating homolog importantly insights leucine linking nevertheless newer nrf2 nrf3 overview shed subcellular zipper
Tagcloud (Intersection) ?