KAT6A and ATN1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT6A	ATN1
Description		lysine acetyltransferase 6A	atrophin 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleosome Nucleus Nucleoplasm Nucleolus Cytosol PML Body Nuclear Speck MOZ/MORF Histone Acetyltransferase Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Perinuclear Region Of Cytoplasm Anchoring Junction
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity Protein-lysine-acetyltransferase Activity DNA-binding Transcription Factor Binding	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Chromatin Organization Nucleosome Assembly Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Acetylation Positive Regulation Of Gene Expression Myeloid Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Developmental Process Chromosome Organization Cellular Senescence Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Hemopoiesis	Negative Regulation Of Transcription By RNA Polymerase II Cell Killing Spermatogenesis Central Nervous System Development Determination Of Adult Lifespan Male Gonad Development Post-embryonic Development Cell Migration Maintenance Of Cell Polarity Response To Food Multicellular Organism Growth Positive Regulation Of DNA-templated Transcription Neuron Apoptotic Process
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation	Regulation of PTEN gene transcription
Drugs
Diseases			Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Sleep duration ( 30531941)	Refractive error ( 32231278)
Interacting Genes		18 interacting genes: AKT1 ATN1 ATXN1 CREBBP H3-4 H3-5 H3C1 H3C14 H4C1 H4C16 H4C9 HEMGN MAFK PML RERE RUNX1 SPI1 UBE2U	126 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CHRD CPAP CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 FXR1 FXR2 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SAXO4 SH3RF1 SHANK3 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 TSC1 USP2 USP54 VIM WDR5 WWP1 WWP2 YAP1 ZMYND8 ZNF503 ZSWIM8
Entrez ID		7994	1822
HPRD ID		03244	06311
Ensembl ID		ENSG00000083168	ENSG00000111676
Uniprot IDs		A5PKX7 A5PLL3 Q92794	P54259 Q86V38
PDB IDs		1M36 2LN0 2OZU 2RC4 3V43 4LJN 4LK9 4LKA 4LLB 5B75 5B76 5B77 5B78 6LSB 7Y43 8DD5 8H7A 9ARR 9DZN 9FKR
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Protein Heterodimerization Activity Nucleosome Nucleoplasm Chromatin Remodeling Nucleosome Assembly Chromatin Organization Nucleosome Organization Protein-DNA Complex Assembly DNA Binding Negative Regulation Of RNA Metabolic Process Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Chromosome, Telomeric Region Negative Regulation Of Megakaryocyte Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Myeloid Cell Differentiation Negative Regulation Of Myeloid Cell Differentiation Chromosome Regulation Of Megakaryocyte Differentiation Telomere Organization Protein Localization To Chromosome, Centromeric Region Regulation Of Cell Differentiation Regulation Of Cell Development Protein-containing Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process Oncogene-induced Cell Senescence Protein Localization To Chromatin Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Organization Regulation Of Multicellular Organismal Development Regulation Of Developmental Process Regulation Of Hemopoiesis Negative Regulation Of Macromolecule Metabolic Process Protein-containing Complex Chromatin Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Fibroblast Migration Protein Localization To Chromosome Transcription Coactivator Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Response To Light Stimulus Nuclear Matrix	Protein Binding Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Developmental Process Extracellular Matrix Structural Constituent Positive Regulation Of Metabolic Process Regulation Of Gene Expression Calcium Ion Binding Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Protein Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Intermediate Filament Transcription Corepressor Activity Regulation Of Protein Stability Elastic Fiber Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Cell Surface Receptor Signaling Pathway Wnt Signaling Pathway System Development Apoptotic Process DNA-binding Transcription Factor Binding Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Programmed Cell Death Cell Death Histone H3 Acetyltransferase Activity Regulation Of Cell Population Proliferation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cell Projection Organization Signal Transduction Positive Regulation Of RNA Metabolic Process
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