CBLL1 and DGCR6

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		CBLL1	DGCR6
Gene Name		Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase	DiGeorge syndrome critical region gene 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex	Proteinaceous Extracellular Matrix Nucleus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Identical Protein Binding	Molecular_function
	Biological Process	Negative Regulation Of Cell Adhesion Single Organismal Cell-cell Adhesion Protein Ubiquitination Positive Regulation Of Cell Migration Positive Regulation Of Endocytosis	Cell Adhesion Organ Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CDC42 CDH1 DGCR6 ESR1 YWHAQ	61 interactors: ADAMTSL4 AES AGTRAP APP ARNT2 C1orf94 C3orf62 CBLL1 CCDC33 CCDC36 CCDC67 CTAGE5 CTBP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 FBF1 GOLGA2 GSE1 HGS HOMEZ IKZF3 KIAA1377 KLHL12 LZTS2 MBIP MEIS2 MEOX2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NL NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPERT SPRY2 SS18L1 TCF12 TCF4 TFIP11 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446
Entrez ID		79872	8214
HPRD ID		07590	03177
Ensembl ID		ENSG00000105879	ENSG00000183628
Uniprot IDs		B4DDV7 Q75N03	Q14129
PDB IDs
Enriched GO Terms of Interacting Partners?		Gland Morphogenesis Epithelial Cell Development Positive Regulation Of Intracellular Transport Organ Morphogenesis Substantia Nigra Development Organ Development Salivary Gland Morphogenesis Salivary Gland Development Neural Nucleus Development Exocrine System Development Regulation Of Intracellular Transport Regulation Of Apoptotic Process Regulation Of Morphogenesis Of A Branching Structure Regulation Of Cell Death Gland Development Epithelial Cell Differentiation Midbrain Development Adherens Junction Organization System Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Brain Development Multicellular Organismal Development Regulation Of Protein Localization Head Development Anatomical Structure Development Positive Regulation Of Cell Proliferation Positive Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Intracellular Protein Transport Anatomical Structure Morphogenesis Regulation Of Organelle Organization Regulation Of Organ Morphogenesis Prostate Epithelial Cord Elongation Submandibular Salivary Gland Formation Actin Filament Branching Central Nervous System Development Developmental Process Cell-cell Junction Organization Regulation Of Cellular Localization Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Signal Transduction Epithelium Development Negative Regulation Of Signal Transduction Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Cellular Response To Indole-3-methanol Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Cell Division Negative Regulation Of Signaling Cell Adhesion	RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Gene Expression Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Binding Regulation Of ERBB Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Death Developmental Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Signal Transduction Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Modification By Small Protein Conjugation Nitrogen Compound Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway
Tagcloud ?		administration basis cadherin casitas cerebral cns cortex e3 entry evidences hakai immunofluorescent labeling ligase lineage localized lps lymphoma might nervous neuroinflammation originally provided re speculated striking transforming ubiquitin unclear	1rn antidopaminergic daao darpp dgcr2 drd2 drd3 dtnbp1 evolves facets forcefully g72 gabra1 gabra6 gabrp gria1 grin1 grm3 merge mglu2 networking prodh rgs4 slc1a2 slc1a6 underpinned unifying vulnerablility zdhhc8
Tagcloud (Difference) ?		administration basis cadherin casitas cerebral cns cortex e3 entry evidences hakai immunofluorescent labeling ligase lineage localized lps lymphoma might nervous neuroinflammation originally provided re speculated striking transforming ubiquitin unclear	1rn antidopaminergic daao darpp dgcr2 drd2 drd3 dtnbp1 evolves facets forcefully g72 gabra1 gabra6 gabrp gria1 grin1 grm3 merge mglu2 networking prodh rgs4 slc1a2 slc1a6 underpinned unifying vulnerablility zdhhc8
Tagcloud (Intersection) ?