DDX56 and EHD2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DDX56	EHD2
Description		DEAD-box helicase 56	EH domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytosol Membrane	Nucleus Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Caveola Endosome Membrane Membrane Endocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity RNA Stem-loop Binding Protein Sequestering Activity	Nucleotide Binding Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Cytoplasmic Pattern Recognition Receptor Signaling Pathway RRNA Processing Protein Import Into Nucleus Positive Regulation Of Neuron Projection Development Negative Regulation Of Type I Interferon Production Ribosome Biogenesis Host-mediated Perturbation Of Viral RNA Genome Replication Defense Response To Virus	Endocytosis Cortical Actin Cytoskeleton Organization Endocytic Recycling Cilium Assembly Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		6 interacting genes: EHD2 EIF4A3 OGT SOX30 USP33 ZNF408	14 interacting genes: AP1M1 AP1M2 AP2M1 BPGM CDC42 DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23
Entrez ID		54606	30846
HPRD ID		12154	10434
Ensembl ID		ENSG00000136271	ENSG00000024422
Uniprot IDs		Q9NY93	Q9NZN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Negative Regulation Of Translation Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Translation Protein O-acetylglucosaminyltransferase Activity Selenocysteine Insertion Sequence Binding Negative Regulation Of Translational Elongation Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Translation At Postsynapse Proacrosomal Vesicle Fusion VCB Complex	Cytosol Intracellular Transport Clathrin Adaptor Complex Cellular Localization Establishment Of Localization In Cell Clathrin Adaptor Activity Clathrin-coated Vesicle Vesicle-mediated Transport Extrinsic Component Of Presynaptic Endocytic Zone Membrane Protein Transport Intracellular Protein Localization Clathrin-coated Pit Establishment Of Protein Localization AP-1 Adaptor Complex Intracellular Protein Transport Regulation Of Endocytosis Regulation Of Vesicle Size Trans-Golgi Network Membrane Regulation Of Receptor-mediated Endocytosis Clathrin-coated Endocytic Vesicle Synaptic Vesicle Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Receptor Internalization Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endocytosis Clathrin-dependent Endocytosis Dendritic Spine Organization Vesicle Budding From Membrane Cytoplasmic Vesicle Membrane Endocytosis Clathrin-coated Vesicle Membrane Vesicle Cytoplasmic Vesicle Extracellular Exosome Neuron Projection Organization Postsynapse Organization Regulation Of Vesicle-mediated Transport Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Positive Regulation Of Receptor-mediated Endocytosis Endosomal Transport Import Into Cell Membrane Organization Receptor Internalization GBD Domain Binding Storage Vacuole Endocytic Vesicle Membrane Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Regulation Of Receptor Internalization
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